Human DKK1 Recombinant Protein (hFc Tag) (HDPT0168)
- SKU:
- HDPT0168
- Product Type:
- Recombinant Protein
- Species:
- Human
- Research Area:
- Immune Checkpoint
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Description
Human DKK1 Recombinant Protein (hFc Tag)
| Description: | This gene encodes a member of the dickkopf family of proteins. Members of this family are secreted proteins characterized by two cysteine-rich domains that mediate protein-protein interactions. The encoded protein binds to the LRP6 co-receptor and inhibits beta-catenin-dependent Wnt signaling. This gene plays a role in embryonic development and may be important in bone formation in adults. Elevated expression of this gene has been observed in numerous human cancers and this protein may promote proliferation, invasion and growth in cancer cell lines. |
| Product name: | Human DKK1 Recombinant Protein (hFc Tag) |
| Synonyms: | DKK-1, SK |
| Type: | protein |
| Size: | 50 µg |
| Name: | DKK1 |
| Origin: | Human |
| Source: | HEK293 |
| Protein Type: | Recombinant |
| Application: | Contact Technical Support |
| Purity: | > 90% |
| Purification: | affinity purification |
| Format: | Lyophilized |
| Conjugate: | C-Human Fc tag |
| Storage: | Store at -80°C for 12 months (Avoid repeated freezing and thawing) |
| Usage: | Research use only |
| Buffer: | Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization. |
| Reconstitution: | Reconstitute with deionized water |
| Sequence: | DKK1（Thr32-His266）+hFc（Glu99-Ala330） |
| Gene ID: | 22943 |
| Uniprot: | O94907 |
| Molecular Weight: | 70 kDa |
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