Human CYGB Recombinant Protein (RPPB3320)
- SKU:
- RPPB3320
- Product Type:
- Recombinant Protein
- Species:
- Human
- Uniprot:
- Q8WWM9
Description
| Product Name: | Human CYGB Recombinant Protein |
| Product Code: | RPPB3320 |
| Size: | 10µg |
| Species: | Human |
| Target: | CYGB |
| Synonyms: | HGB, STAP, Cytoglobin, CYGB. |
| Source: | Escherichia Coli |
| Physical Appearance: | Sterile filtered colorless solution. |
| Formulation: | CYGB protein solution (1mg/ml) containing 20mM Tris-HCl buffer (pH8.0) and 10% glycerol. |
| Stability: | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. |
| Purity: | Greater than 90.0% as determined by SDS-PAGE. |
| Amino Acid Sequence: | MGSSHHHHHH SSGLVPRGSH MEKVPGEMEI ERRERSEELS EAERKAVQAM WARLYASCED VGVAILVRFF VNFPSAKQYF SQFKHMEDPL EMERSPQLRK HACRVMGALN TVVENLHDPD KVSSVLALVG KAHALKHKVE PVYFKILSGV ILEVVAEEFA SDFPPETQRA WAKLRGLIYS HVTAAYKEVG WVQQVPNATT PPATLPSSGP |
Cytoglobin is a globin protein found in the brain and is mainly utilized in marine mammals. CYGB acts a a protector under conditions of hypoxia. The suggested function of CYGB is the modulation of oxygen and nitric oxide metabolism or scavenging free radicals within a cell.
CYGB Recombinant Human produced in E.Coli is a single, non-glycosylated polypeptide chain containing 210 amino acids (1-190 a.a.) and having a molecular mass of 23.5kDa. The CYGB is fused to a 20 amino acid His-Tag at N-terminus and purified by proprietary chromatographic techniques.
| UniProt Protein Function: | CYGB: May have a protective function during conditions of oxidative stress. May be involved in intracellular oxygen storage or transfer. Belongs to the globin family. |
| UniProt Protein Details: | Chromosomal Location of Human Ortholog: 17q25 Cellular Component: cytosol Molecular Function:nitric oxide dioxygenase activity; peroxidase activity; protein binding Biological Process: regulation of nitric-oxide synthase activity; response to oxidative stress |
| NCBI Summary: | This gene encodes a globin protein found in vertebrate cells. The encoded protein is described as a hexacoordinate hemoglobin which binds ligand differently from the pentacoordinate hemoglobins involved in oxygen transport, and may be involved in protection during oxidative stress. This gene is located on chromosome 17 in the same region as a retinal gene which is mutated in progressive rod-cone degeneration, but in the opposite orientation. [provided by RefSeq, Jan 2012] |
| UniProt Code: | Q8WWM9 |
| NCBI GenInfo Identifier: | 21263504 |
| NCBI Gene ID: | 114757 |
| NCBI Accession: | Q8WWM9.1 |
| UniProt Secondary Accession: | Q8WWM9,Q541Y7, Q8N2X5, |
| UniProt Related Accession: | Q8WWM9 |
| Molecular Weight: | 21,405 Da |
| NCBI Full Name: | Cytoglobin |
| NCBI Synonym Full Names: | cytoglobin |
| NCBI Official Symbol: | CYGB�� |
| NCBI Official Synonym Symbols: | HGB; STAP�� |
| NCBI Protein Information: | cytoglobin |
| UniProt Protein Name: | Cytoglobin |
| UniProt Synonym Protein Names: | Histoglobin; HGb; Stellate cell activation-associated protein |
| Protein Family: | Cytoglobin |
| UniProt Gene Name: | CYGB�� |
| UniProt Entry Name: | CYGB_HUMAN |
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