Human CYB5R1 Recombinant Protein (RPPB1529)
- SKU:
- RPPB1529
- Product Type:
- Recombinant Protein
- Species:
- Human
- Uniprot:
- Q9UHQ9
- Research Area:
- Enzymes
Description
| Product Name: | Human CYB5R1 Recombinant Protein |
| Product Code: | RPPB1529 |
| Size: | 20µg |
| Species: | Human |
| Target: | CYB5R1 |
| Synonyms: | B5R.1, B5R1, B5R2, humb5R2, NQO3A2, NADH-cytochrome b5 reductase 1, CYB5R1, NAD (P) H: quinone oxidoreductase type 3 polypeptide A2. |
| Source: | Escherichia Coli |
| Physical Appearance: | Sterile Filtered colorless solution. |
| Formulation: | The CYB5R1 solution (0.5mg/ml) contains 20mM Tris-HCl buffer (pH 8.0), 0.15M NaCl, 10% glycerol and 1mM DTT. |
| Stability: | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. |
| Purity: | Greater than 85% as determined by SDS-PAGE. |
| Amino Acid Sequence: | MGSSHHHHHH SSGLVPRGSH MGSLVRRSRR PQVTLLDPNE KYLLRLLDKT TVSHNTKRFR FALPTAHHTL GLPVGKHIYL STRIDGSLVI RPYTPVTSDE DQGYVDLVIK VYLKGVHPKF PEGGKMSQYL DSLKVGDVVE FRGPSGLLTY TGKGHFNIQP NKKSPPEPRV AKKLGMIAGG TGITPMLQLI RAILKVPEDP TQCFLLFANQ TEKDIILRED LEELQARYPN RFKLWFTLDH PPKDWAYSKG FVTADMIREH LPAPGDDVLV LLCGPPPMVQ LACHPNLDKL GYSQKMRFTY |
Cytochrome b5 reductase 1 (CYB5R1) is a part of the flavoprotein pyridine nucleotide cytochrome reductase family. CYB5R1 is engaged in desaturation and elongation of fatty acids, cholesterol biosynthesis, drug metabolism, and, in erythrocyte, methemoglobin decrease.
CYB5R1 Human Recombinant produced in E.coli is a single, non-glycosylated polypeptide chain containing 300 amino acids (29-305) and having a molecular mass of 33.8kDa. CYB5R1 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
| UniProt Protein Function: | CYB5R1: NADH-cytochrome b5 reductases are involved in desaturation and elongation of fatty acids, cholesterol biosynthesis, drug metabolism, and, in erythrocyte, methemoglobin reduction. Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. |
| UniProt Protein Details: | Protein type:Oxidoreductase; Carbohydrate Metabolism - amino sugar and nucleotide sugar; EC 1.6.2.2; Membrane protein, integral Chromosomal Location of Human Ortholog: 1q32.1 Cellular Component: membrane; mitochondrion; integral to membrane Molecular Function:cytochrome-b5 reductase activity Biological Process: sterol biosynthetic process |
| UniProt Code: | Q9UHQ9 |
| NCBI GenInfo Identifier: | 49574502 |
| NCBI Gene ID: | 51706 |
| NCBI Accession: | NP_057327 |
| UniProt Secondary Accession: | Q9UHQ9,O95329, Q53F73, Q8NCL5, Q9UHJ1, A0PK21, B2R8E0 |
| UniProt Related Accession: | Q9UHQ9 |
| Molecular Weight: | 34,095 Da |
| NCBI Full Name: | NADH-cytochrome b5 reductase 1 |
| NCBI Synonym Full Names: | cytochrome b5 reductase 1 |
| NCBI Official Symbol: | CYB5R1�� |
| NCBI Official Synonym Symbols: | B5R1; B5R2; B5R.1; NQO3A2; humb5R2�� |
| NCBI Protein Information: | NADH-cytochrome b5 reductase 1 |
| UniProt Protein Name: | NADH-cytochrome b5 reductase 1 |
| UniProt Synonym Protein Names: | Humb5R2; NAD(P)H:quinone oxidoreductase type 3 polypeptide A2 |
| UniProt Gene Name: | CYB5R1�� |
| UniProt Entry Name: | NB5R1_HUMAN |
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