Human CXC-R3 Recombinant Protein (hFc Tag) (HDPT0233)
- SKU:
- HDPT0233
- Product Type:
- Recombinant Protein
- Species:
- Human
- Research Area:
- Immune Checkpoint
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Description
Human CXC-R3 Recombinant Protein (hFc Tag)
| Description: | This gene encodes a G protein-coupled receptor with selectivity for three chemokines, termed CXCL9/Mig (monokine induced by interferon-g), CXCL10/IP10 (interferon-g-inducible 10 kDa protein) and CXCL11/I-TAC (interferon-inducible T cell a-chemoattractant). Binding of chemokines to this protein induces cellular responses that are involved in leukocyte traffic, most notably integrin activation, cytoskeletal changes and chemotactic migration. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. One of the isoforms (CXCR3-B) shows high affinity binding to chemokine, CXCL4/PF4 (PMID:12782716). |
| Product name: | Human CXC-R3 Recombinant Protein (hFc Tag) |
| Synonyms: | C-X-C chemokine receptor type 3,CXC-R3,CXCR-3,CKR-L2，G protein-coupled receptor 9，CD183，IP-10 receptor |
| Type: | protein |
| Size: | 50 µg |
| Name: | CXC-R3 |
| Origin: | Human |
| Source: | HEK293 |
| Protein Type: | Recombinant |
| Application: | Contact Technical Support |
| Purity: | Contact Technical Support |
| Purification: | affinity purification |
| Format: | Lyophilized |
| Conjugate: | C-Human Fc |
| Storage: | Store at -80°C for 12 months (Avoid repeated freezing and thawing) |
| Usage: | Research use only |
| Buffer: | Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization. |
| Reconstitution: | Reconstitute with deionized water |
| Sequence: | CXC-R3(Met1-Arg53)+hFc(Glu99-Ala330) |
| Gene ID: | |
| Uniprot: | P49682 |
| Molecular Weight: | 31.35 kDa |
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