Human CUTC Recombinant Protein (RPPB3314)
- SKU:
- RPPB3314
- Product Type:
- Recombinant Protein
- Species:
- Human
- Uniprot:
- Q9NTM9
Frequently bought together:
Description
| Product Name: | Human CUTC Recombinant Protein |
| Product Code: | RPPB3314 |
| Size: | 20µg |
| Species: | Human |
| Target: | CUTC |
| Synonyms: | Copper homeostasis protein cutC homolog, CUTC, CGI-32, RP11-483F11.3. |
| Source: | Escherichia Coli |
| Physical Appearance: | Sterile filtered colorless solution. |
| Formulation: | CUTC protein solution (0.5mg/ml) containing 20mM Tris-HCl buffer (pH 8.0), 5mM DTT, 10% glycerol and 200mM NaCl. |
| Stability: | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. |
| Purity: | Greater than 95.0% as determined by SDS-PAGE. |
| Amino Acid Sequence: | MGSSHHHHHH SSGLVPRGSH MKRQGASSER KRARIPSGKA GAANGFLMEV CVDSVESAVN AERGGADRIE LCSGLSEGGT TPSMGVLQVV KQSVQIPVFV MIRPRGGDFL YSDREIEVMK ADIRLAKLYG ADGLVFGALT EDGHIDKELC MSLMAICRPL PVTFHRAFDM VHDPMAALET LLTLGFERVL TSGCDSSALE GLPLIKRLIE QAKGRIVVMP GGGITDRNLQ RILEGSGATE FHCSARSTRD SGMKFRNSSV AMGASLSCSE YSLKVTDVTK VRTLNAIAKN ILV |
CUTC belongs to the Cut family and may be involved in efflux trafficking of cuprous ion. The Cut family is linked with the copper homeostasis and involved in several vital metabolisms, such as uptake, storage, delivery, and efflux of copper. Copper which is an essential heavy metal trace element has an imperative role in cell physiology.
CUTC Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 293 amino acids (1-273 a.a) and having a molecular mass of 31.5kDa.CUTC is fused to a 20 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
| UniProt Protein Function: | CUTC: a copper binding protein associated with copper homeostasis and transport. Widely expressed in human tissues. Its nuclear and cytoplasmic distribution suggests that it may be a nucleocytoplasmic copper ion shuttle protein.Protein type: CarrierChromosomal Location of Human Ortholog: 10q24.2Cellular Component: cytoplasm; nucleolus; nucleusMolecular Function: copper ion binding; protein bindingBiological Process: protein tetramerization |
| UniProt Protein Details: | |
| NCBI Summary: | Members of the CUT family of copper transporters are associated with copper homeostasis and are involved in the uptake, storage, delivery, and efflux of copper (Gupta et al., 1995 [PubMed 7635807]; Li et al., 2005 [PubMed 16182249]).[supplied by OMIM, Mar 2008] |
| UniProt Code: | Q9NTM9 |
| NCBI GenInfo Identifier: | 54035909 |
| NCBI Gene ID: | 51076 |
| NCBI Accession: | Q9NTM9.1 |
| UniProt Secondary Accession: | Q9NTM9,Q5TCZ8, Q9Y321 |
| UniProt Related Accession: | Q9NTM9 |
| Molecular Weight: | 29,341 Da |
| NCBI Full Name: | Copper homeostasis protein cutC homolog |
| NCBI Synonym Full Names: | cutC copper transporter |
| NCBI Official Symbol: | CUTC�� |
| NCBI Official Synonym Symbols: | CGI-32�� |
| NCBI Protein Information: | copper homeostasis protein cutC homolog |
| UniProt Protein Name: | Copper homeostasis protein cutC homolog |
| UniProt Synonym Protein Names: | |
| Protein Family: | CutC-like protein |
| UniProt Gene Name: | CUTC�� |
| UniProt Entry Name: | CUTC_HUMAN |
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