Human CSN2 Recombinant Protein (RPPB3277)
- SKU:
- RPPB3277
- Product Type:
- Recombinant Protein
- Species:
- Human
- Uniprot:
- P05814
Description
| Product Name: | Human CSN2 Recombinant Protein |
| Product Code: | RPPB3277 |
| Size: | 10µg |
| Species: | Human |
| Target: | CSN2 |
| Synonyms: | Beta-casein, CSN2, CASB. |
| Source: | Escherichia Coli |
| Physical Appearance: | Sterile Filtered clear solution. |
| Formulation: | CSN2 protein solution (0.25mg/ml) containing 20mM Tris-HCl buffer (pH8.0), 10% glycerol, 0.5M NaCl, 0.25M imidazole, 1mM DTT and 0.1mM PMSF. |
| Stability: | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. |
| Purity: | Greater than 95.0% as determined by SDS-PAGE. |
| Amino Acid Sequence: | MGSSHHHHHH SSGLVPRGSH MGSHMRETIE SLSSSEESIT EYKQKVEKVK HEDQQQGEDE HQDKIYPSFQ PQPLIYPFVE PIPYGFLPQN ILPLAQPAVV LPVPQPEIME VPKAKDTVYT KGRVMPVLKS PTIPFFDPQI PKLTDLENLH LPLPLLQPLM QQVPQPIPQT LALPPQPLWSVPQPKVLPIP QQVVPYPQRA VPVQALLLNQ ELLLNPTHQI YPVTQPLAPV HNPISV |
Beta-casein precursor (CSN2) is a member of the beta-casein family. CSN2 has an imperative role in determination of the surface properties of the casein micelles. CSN2 is specific to mammary glands and is secreted in milk.
CSN2 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 236 amino acids (16-226 a.a.) and having a molecular mass of 26.6kDa.CSN2 is fused to a 25 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
| UniProt Protein Function: | CSN2: Important role in determination of the surface properties of the casein micelles. Belongs to the beta-casein family. |
| UniProt Protein Details: | Protein type:Calcium-binding; Inhibitor; Secreted; Secreted, signal peptide Chromosomal Location of Human Ortholog: 4q13.3 Cellular Component: extracellular region; extracellular space Molecular Function:calcium ion binding; cysteine protease inhibitor activity; enzyme inhibitor activity Biological Process: calcium ion transport; lactation |
| NCBI Summary: | This gene is a member of the beta casein family. There are two types of casein protein, beta (encoded by this gene) and kappa, both of which are secreted in human milk. Beta casein is the principal protein in human milk and the primary source of essential amino acids for a suckling infant. Beta and kappa casein proteins acting together form spherical micelles which bind within them important dietary minerals, such as calcium and phosphorous. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2014] |
| UniProt Code: | P05814 |
| NCBI GenInfo Identifier: | 115661 |
| NCBI Gene ID: | 1447 |
| NCBI Accession: | P05814.4 |
| UniProt Secondary Accession: | P05814,Q4VAZ9, Q9UCM5, |
| UniProt Related Accession: | P05814 |
| Molecular Weight: | 25kDa |
| NCBI Full Name: | Beta-casein |
| NCBI Synonym Full Names: | casein beta |
| NCBI Official Symbol: | CSN2�� |
| NCBI Official Synonym Symbols: | CASB�� |
| NCBI Protein Information: | beta-casein |
| UniProt Protein Name: | Beta-casein |
| Protein Family: | COP9 signalosome complex |
| UniProt Gene Name: | CSN2�� |
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