Nanodisc Human CLDN9-Strep Protein (HDFP818)
- SKU:
- HDFP818
- Size:
- 10μg
- Target:
- CLDN9
- Tag:
- C-Flag&Strep Tag
- Expression Host:
- HEK293
- Conjugate:
- Unconjugated
Frequently bought together:
Description
| Product Name: | Nanodisc Human CLDN9-Strep Protein |
| SKU: | HDFP818 |
| Size: | 10μg |
| Target: | CLDN9 |
| Tag: | C-Flag&Strep Tag |
| Expression Host: | HEK293 |
| Conjugate: | Unconjugated |
| Synonyms: | DFNB116 |
| Protein Families: | Transmembrane. |
| Protein Description: | Human CLDN9-Strep full length protein-synthetic nanodisc |
| Protein Pathways: | Cell adhesion molecules (CAMs), Leukocyte transendothelial migration, Tight junction. |
| Molecular Weight: | The human full length CLDN9-Strep protein has a MW of 22.8 kDa |
This protein is a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. This protein is one of the entry cofactors for hepatitis C virus. Mouse studies revealed that this gene is required for the preservation of sensory cells in the hearing organ and the gene deficiency is associated with deafness.
| Uniprot ID: | O95484 |
| Formulation & Reconstitution: | Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions. Do not use solvents with a pH below 6.5 or those containing high concentrations of divalent metal ions (greater than 5 mM) in subsequent experiments. |
| Storage & Shipping: | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C(Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| Usage: | Research use only |
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