Human CLDN5 Full-Length Bioactive Membrane Protein (HDFP060)
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- SKU:
- HDFP060
- Product Type:
- Recombinant Protein
- Protein Type:
- Full-Length Bioactive Membrane Protein
- Species:
- Human
- Uniprot:
- O00501
Description
system_update_altDatasheet
| Product name | Human CLDN5 full length protein-synthetic nanodisc |
| Size: | 10ug |
| Product SKU: | HDFP060 |
| Product Category | Full Length Transmembrane Proteins |
| Target: | CLDN5 |
| Uniprot: | O00501 |
| Description: | Human CLDN5 full length protein-synthetic nanodisc |
| Molecular Weight: | The human full length CLDN5 protein has a MW of 31.4 kDa |
| Protein Family: | Transmembrane |
| Protein Pathways: | Cell adhesion molecules (CAMs), Leukocyte transendothelial migration, Tight junction |
| Storage & Shipping: | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| Synonyms: | AWAL; BEC1; CPETRL1; TMDVCF; TMVCF |
| Expression System: | HEK293 |
| Formulation: | Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions. |
| Background: | This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets. Mutations in this gene have been found in patients with velocardiofacial syndrome. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, May 2018] |
| Delivery: | 3-4 weeks |
| Usage | Research use only |
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