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Human CLDN4 Full-Length Bioactive Membrane Protein (HDFP064)

SKU:
HDFP064
Product Type:
Recombinant Protein
Protein Type:
Full-Length Bioactive Membrane Protein
Species:
Human
Uniprot:
O14493
$1,663
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Description

system_update_altDatasheet
Product nameHuman CLDN4 full length protein-synthetic nanodisc
Size:10ug
Product SKU:HDFP064
Product CategoryFull Length Transmembrane Proteins
Target:CLDN4
Uniprot:O14493
Description:Human CLDN4 full length protein-synthetic nanodisc
Molecular Weight:The human full length CLDN4 protein has a MW of 22.1 kDa
Protein Family:Druggable Genome, Transmembrane
Protein Pathways:Cell adhesion molecules (CAMs), Leukocyte transendothelial migration, Tight junction
Storage & Shipping:Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Synonyms:CPE-R; CPER; CPETR; CPETR1; hCPE-R; WBSCR8
Expression System:HEK293
Formulation:Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions.
Background:The protein encoded by this intronless gene belongs to the claudin family. Claudins are integral membrane proteins that are components of the epithelial cell tight junctions, which regulate movement of solutes and ions through the paracellular space. This protein is a high-affinity receptor for Clostridium perfringens enterotoxin (CPE) and may play a role in internal organ development and function during pre- and postnatal life. This gene is deleted in Williams-Beuren syndrome, a neurodevelopmental disorder affecting multiple systems. [provided by RefSeq, Sep 2013]
Delivery:3-4 weeks
UsageResearch use only

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