Human CHAC2 Recombinant Protein (RPPB3163)
- SKU:
- RPPB3163
- Product Type:
- Recombinant Protein
- Species:
- Human
- Uniprot:
- Q8WUX2
Frequently bought together:
Description
| Product Name: | Human CHAC2 Recombinant Protein |
| Product Code: | RPPB3163 |
| Size: | 10µg |
| Species: | Human |
| Target: | CHAC2 |
| Synonyms: | ChaC Cation Transport Regulator Homolog 2 (E. Coli), ChaC Cation Transport Regulator-Like 2 (E. Coli), Gamma-GCT Acting On Glutathione Homolog 2. |
| Source: | Escherichia Coli |
| Physical Appearance: | Sterile Filtered clear solution. |
| Formulation: | The CHAC2 solution (0.5mg/ml) contains 20mM Tris-HCl buffer (pH 8.0), 1mM DTT, 100mM NaCl and 10% glycerol. |
| Stability: | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. |
| Purity: | Greater than 90% as determined by SDS-PAGE. |
| Amino Acid Sequence: | MGSSHHHHHH SSGLVPRGSH MGSMWVFGYG SLIWKVDFPY QDKLVGYITN YSRRFWQGST DHRGVPGKPG RVVTLVEDPA GCVWGVAYRL PVGKEEEVKA YLDFREKGGY RTTTVIFYPK DPTTKPFSVL LYIGTCDNPD YLGPAPLEDI AEQIFNAAGP SGRNTEYLFE LANSIRNLVP EEADEHLFAL EKLVKERLEG KQNLNCI |
Cation transport regulator-like protein 2 (CHAC2) is a member of the chaC family.�Catalyzes the cleavage glutathione into 5-oxoproline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides.
CHAC2 Human Recombinant produced in E.coli is a single, non-glycosylated polypeptide chain containing 207 amino acids (1-184) and having a molecular mass of 23.3 kDa. CHAC2 is fused to a 23 amino acid His-tag at N-terminus.
| UniProt Protein Function: | CHAC2: Belongs to the chaC family.Chromosomal Location of Human Ortholog: 2p16Cellular Component: cytosolMolecular Function: gamma-glutamylcyclotransferase activityBiological Process: glutathione biosynthetic process |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | Q8WUX2 |
| NCBI GenInfo Identifier: | 74730779 |
| NCBI Gene ID: | 494143 |
| NCBI Accession: | Q8WUX2.1 |
| UniProt Secondary Accession: | Q8WUX2,Q8WVI8 |
| UniProt Related Accession: | Q8WUX2 |
| Molecular Weight: | 20,875 Da |
| NCBI Full Name: | Putative glutathione-specific gamma-glutamylcyclotransferase 2 |
| NCBI Synonym Full Names: | ChaC cation transport regulator homolog 2 |
| NCBI Official Symbol: | CHAC2�� |
| NCBI Official Synonym Symbols: | |
| NCBI Protein Information: | putative glutathione-specific gamma-glutamylcyclotransferase 2 |
| UniProt Protein Name: | Putative glutathione-specific gamma-glutamylcyclotransferase 2 |
| UniProt Synonym Protein Names: | Cation transport regulator-like protein 2 |
| Protein Family: | |
| UniProt Gene Name: | CHAC2�� |
| UniProt Entry Name: | CHAC2_HUMAN |
