Description
Product Name: | Nanodisc Human CELR2 Protein |
SKU: | HDFP213 |
Size: | 10μg |
Target: | CELR2 |
Tag: | C-Flag Tag |
Expression Host: | HEK293 |
Conjugate: | Unconjugated |
Synonyms: | ADGRC2, CDHF10, EGFL2, Flamingo1, MEGF3 |
Protein Families: | Transmembrane, Druggable Genome. |
Protein Description: | Human CELR2 full length protein-synthetic nanodisc |
Protein Pathways: | GPCRDB Other. |
Molecular Weight: | The human full length CELR2 protein has a MW of 317.5kDa |
The protein encoded by this gene is a member of the flamingo subfamily, part of the cadherin superfamily. The flamingo subfamily consists of nonclassic-type cadherins; a subpopulation that does not interact with catenins. The flamingo cadherins are located at the plasma membrane and have nine cadherin domains, seven epidermal growth factor-like repeats and two laminin A G-type repeats in their ectodomain. They also have seven transmembrane domains, a characteristic unique to this subfamily. It is postulated that these proteins are receptors involved in contact-mediated communication, with cadherin domains acting as homophilic binding regions and the EGF-like domains involved in cell adhesion and receptor-ligand interactions. The specific function of this particular member has not been determined. [provided by RefSeq, Jul 2008]
Uniprot ID: | Q9HCU4 |
Formulation & Reconstitution: | Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions. Do not use solvents with a pH below 6.5 or those containing high concentrations of divalent metal ions (greater than 5 mM) in subsequent experiments. |
Storage & Shipping: | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
Usage: | Research use only |