Human CEACAM-1 Recombinant Protein (hFc Tag) (HDPT0231)
- SKU:
- HDPT0231
- Product Type:
- Recombinant Protein
- Species:
- Human
- Research Area:
- Immune Checkpoint
Frequently bought together:
Description
Human CEACAM-1 Recombinant Protein (hFc Tag)
| Description: | This gene encodes a member of the carcinoembryonic antigen (CEA) gene family, which belongs to the immunoglobulin superfamily. Two subgroups of the CEA family, the CEA cell adhesion molecules and the pregnancy-specific glycoproteins, are located within a 1.2 Mb cluster on the long arm of chromosome 19. Eleven pseudogenes of the CEA cell adhesion molecule subgroup are also found in the cluster. The encoded protein was originally described in bile ducts of liver as biliary glycoprotein. Subsequently, it was found to be a cell-cell adhesion molecule detected on leukocytes, epithelia, and endothelia. The encoded protein mediates cell adhesion via homophilic as well as heterophilic binding to other proteins of the subgroup. Multiple cellular activities have been attributed to the encoded protein, including roles in the differentiation and arrangement of tissue three-dimensional structure, angiogenesis, apoptosis, tumor suppression, metastasis, and the modulation of innate and adaptive immune responses. Multiple transcript variants encoding different isoforms have been reported, but the full-length nature of all variants has not been defined. |
| Product name: | Human CEACAM-1 Recombinant Protein (hFc Tag) |
| Synonyms: | CEACAM1,CD66a,BGP,BGP1,BGPI |
| Type: | protein |
| Size: | 50 µg |
| Name: | CEACAM-1 |
| Origin: | Human |
| Source: | HEK293 |
| Protein Type: | Recombinant |
| Application: | Contact Technical Support |
| Purity: | Contact Technical Support |
| Purification: | affinity purification |
| Format: | Lyophilized |
| Conjugate: | C-Human Fc |
| Storage: | Store at -80°C for 12 months (Avoid repeated freezing and thawing) |
| Usage: | Research use only |
| Buffer: | Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization. |
| Reconstitution: | Reconstitute with deionized water |
| Sequence: | CEACAM-1(Gln35-Gly428)+hFc(Glu99-Ala330) |
| Gene ID: | |
| Uniprot: | P13688 |
| Molecular Weight: | 57.86 kDa |
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