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PE/Cyanine7 Anti-Human CD95 Antibody [DX2] (AGEL1841)

SKU:
AGEL1841
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Applications:
FC
Reactivity:
Human
Host Species:
Mouse
Isotype:
IgG2a,k
Clone:
DX2
Conjugation:
PE/Cy7
€249 - €829
Frequently bought together:

Description

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PE/Cyanine7 Anti-Human CD95 Antibody [DX2]

The Human CD95 Monoclonal Antibody (PE/Cyanine7 Conjugated) is a specialized tool for researchers investigating CD95, a cell surface receptor known for its role in apoptosis, or programmed cell death. This monoclonal antibody, designated DX2 (AGEL1841), is engineered for high specificity and sensitivity in detecting CD95 in human samples using flow cytometry techniques. By being conjugated with PE/Cyanine7, this antibody allows for easy visualization and quantification of CD95-expressing cells in a variety of experimental settings.CD95, also referred to as Fas or Apo-1, is a key player in the regulation of cell death processes and immune system function.

Its interactions with ligands trigger apoptotic pathways that are essential for tissue homeostasis and immune response modulation. Studies involving CD95 are crucial for understanding conditions such as cancer, autoimmune diseases, and infectious disorders where abnormal cell death signaling may occur. This monoclonal antibody provides a reliable tool for exploring the role of CD95 in these contexts, aiding in the advancement of research aimed at developing targeted therapies and understanding disease mechanisms.

Product Title:PE/Cyanine7 Anti-Human CD95 Antibody [DX2]
SKU:AGEL1841
Size:20 Tests, 100 Tests, 200 Tests
Clone No:DX2
Synonyms:APT1;FAS1;TNFRSF6;Apo-1 antigen;FASLG receptor;
Host Species:Mouse
Reactivity:Human
Application:FCM
Isotype:Mouse IgG1, κ
Isotype Control:PE/Cyanine7 Mouse IgG1, κ Isotype Control[MOPC-21]
Form:Liquid
Conjugation:PE/Cyanine 7
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P25445
Gene ID:355
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD95 is a 45 kD single chain type I glycoprotein also known as Fas, APO-1, and TNFRSF6. It is a member of the TNF receptor superfamily. CD95 is expressed on T and B lymphocytes, monocytes, neutrophils, and fibroblasts. CD95 expression is upregulated by activation. The extracellular region of CD95 binds to CD178 (Fas ligand). CD178 binding to CD95 induces apoptosis and has been shown to play a role in the maintenance of peripheral tolerance.

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