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PE Anti-Human CD95 Antibody [DX2] (AGEL1838)

SKU:
AGEL1838
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Applications:
FC
Reactivity:
Human
Host Species:
Mouse
Isotype:
IgG2a,k
Clone:
DX2
Conjugation:
PE
€189 - €729
Frequently bought together:

Description

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PE Anti-Human CD95 Antibody [DX2]

The Human CD95 Monoclonal Antibody (PE Conjugated) DX2 (AG-EL1838) offered by Assay Genie is a cutting-edge tool for research focused on CD95, a cell surface receptor known for its role in apoptosis and immune regulation. This monoclonal antibody, conjugated to phycoerythrin for fluorescent labeling, is specifically designed for use in flow cytometry applications for the detection and analysis of CD95 expression in human samples.CD95, also referred to as Fas receptor, is a key player in programmed cell death and plays a crucial role in immune system regulation. Its dysregulation has been implicated in various diseases, including autoimmune disorders and cancer.

Understanding the expression and function of CD95 is essential for unraveling its involvement in disease pathogenesis and for developing targeted therapies.The PE-conjugated DX2 antibody provided by Assay Genie offers high sensitivity and specificity for the detection of CD95, making it an invaluable tool for researchers studying apoptosis, immune responses, and related pathways. With its validated performance in flow cytometry experiments, this antibody enables accurate and reliable assessment of CD95 expression levels in various cell types, paving the way for advancements in immunology, oncology, and beyond.

Product Title:PE Anti-Human CD95 Antibody [DX2]
SKU:AGEL1838
Size:20 Tests, 100 Tests, 200 Tests
Clone No:DX2
Synonyms:APT1;FAS1;TNFRSF6;Apo-1 antigen;FASLG receptor;
Host Species:Mouse
Reactivity:Human
Application:FCM
Isotype:Mouse IgG1, κ
Isotype Control:PE Mouse IgG1, κ Isotype Control[MOPC-21]
Form:Liquid
Conjugation:PE
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P25445
Gene ID:355
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD95 is a 45 kD single chain type I glycoprotein also known as Fas, APO-1, and TNFRSF6. It is a member of the TNF receptor superfamily. CD95 is expressed on T and B lymphocytes, monocytes, neutrophils, and fibroblasts. CD95 expression is upregulated by activation. The extracellular region of CD95 binds to CD178 (Fas ligand). CD178 binding to CD95 induces apoptosis and has been shown to play a role in the maintenance of peripheral tolerance.

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