The Human CD95 Monoclonal Antibody FITC Conjugated (DX2) is a powerful tool for researchers studying CD95, a key cell surface receptor involved in apoptosis and immune response regulation. This antibody, produced through cutting-edge technology, specifically targets the human CD95 protein and is conjugated with FITC for easy detection in flow cytometry and fluorescent microscopy experiments.CD95, also known as Fas receptor, plays a pivotal role in programmed cell death and immune system function. Its dysregulation is implicated in various diseases, including cancer and autoimmune disorders, making it a significant target for therapeutic interventions. By utilizing the Human CD95 Monoclonal Antibody FITC Conjugated (DX2), researchers can effectively explore the expression and functionality of CD95 in different cell types and tissues, advancing our understanding of its role in health and disease.
This antibody is rigorously tested and validated for its specificity and sensitivity in detecting CD95, ensuring reliable and reproducible results in experimental settings. Whether investigating apoptotic pathways, immune cell interactions, or disease mechanisms, the Human CD95 Monoclonal Antibody FITC Conjugated (DX2) from AssayGenie is a valuable resource for cutting-edge research in immunology, oncology, and beyond.
Product Title:
FITC Anti-Human CD95 Antibody [DX2]
SKU:
AGEL1837
Size:
20 Tests, 100 Tests, 200 Tests
Clone No:
DX2
Synonyms:
APT1;FAS1;TNFRSF6;Apo-1 antigen;FASLG receptor;
Host Species:
Mouse
Reactivity:
Human
Application:
FCM
Isotype:
Mouse IgG1, κ
Isotype Control:
FITC Mouse IgG1, κ Isotype Control[MOPC-21]
Form:
Liquid
Conjugation:
FITC
Recommended Use:
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P25445
Gene ID:
355
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD95 is a 45 kD single chain type I glycoprotein also known as Fas, APO-1, and TNFRSF6. It is a member of the TNF receptor superfamily. CD95 is expressed on T and B lymphocytes, monocytes, neutrophils, and fibroblasts. CD95 expression is upregulated by activation. The extracellular region of CD95 binds to CD178 (Fas ligand). CD178 binding to CD95 induces apoptosis and has been shown to play a role in the maintenance of peripheral tolerance.