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GenieFluor 488 Anti-Human CD95 Antibody [DX2] (AGEL1842)

SKU:
AGEL1842
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Applications:
FC
€249 - €829
Frequently bought together:

Description

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GenieFluor 488 Anti-Human CD95 Antibody [DX2]

The Human CD95 Monoclonal Antibody (AF488-conjugated, DX2) is a powerful tool for researchers delving into the realm of apoptosis and cell death pathways. This antibody, tagged with AF488 for fluorescence applications, specifically targets the CD95 protein, also known as Fas or APO-1. CD95 is a cell surface receptor known for its role in initiating apoptosis and regulating immune responses.The high specificity and reactivity of this monoclonal antibody make it an excellent choice for experiments involving human samples. Its conjugation with AF488 allows for visualizing and tracking the CD95 protein in various cell types and tissues, providing valuable insights into its function and localization.

Researchers in the fields of molecular biology, cell biology, and immunology can benefit from the precise detection capabilities of this antibody.By studying the CD95 receptor and its signaling pathways, researchers can uncover new insights into the mechanisms of cell death, immune regulation, and disease progression. This antibody is a valuable tool for exploring the role of CD95 in conditions such as cancer, autoimmune disorders, and infectious diseases. Harnessing the potential of CD95 modulation may open up avenues for developing novel therapeutic strategies targeting cell death pathways and immune responses.

Product Title:GenieFluor 488 Anti-Human CD95 Antibody [DX2]
SKU:AGEL1842
Size:20 Tests, 100 Tests, 200 Tests
Clone No:DX2
Synonyms:APT1;FAS1;TNFRSF6;Apo-1 antigen;FASLG receptor;
Host Species:Mouse
Reactivity:Human
Application:FCM
Isotype:Mouse IgG1, κ
Isotype Control:Genie Fluor 488 Mouse IgG1, κ Isotype Control[MOPC-21]
Form:Liquid
Conjugation:Genie Fluor488
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P25445
Gene ID:355
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD95 is a 45 kD single chain type I glycoprotein also known as Fas, APO-1, and TNFRSF6. It is a member of the TNF receptor superfamily. CD95 is expressed on T and B lymphocytes, monocytes, neutrophils, and fibroblasts. CD95 expression is upregulated by activation. The extracellular region of CD95 binds to CD178 (Fas ligand). CD178 binding to CD95 induces apoptosis and has been shown to play a role in the maintenance of peripheral tolerance.

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