The Human CD90 Monoclonal Antibody (APC Conjugated, 5E10) is a cutting-edge tool for researchers investigating the role of CD90, a cell surface marker widely used in immunophenotyping and stem cell research. This monoclonal antibody, clone 5E10, offers high specificity and sensitivity for human samples, making it an essential tool for flow cytometry and immunophenotyping studies.CD90, also known as Thy-1, is a glycoprotein involved in cell-to-cell interaction, signaling pathways, and cell migration. Its expression is commonly associated with stem cells, T cells, and cancer stem cells. The APC conjugation of this monoclonal antibody allows for easy and efficient detection of CD90 in flow cytometry experiments, providing valuable insights into cell populations and their characteristics.
Researchers in the fields of immunology, stem cell biology, and cancer research will find this APC-conjugated CD90 monoclonal antibody indispensable for their studies. Its reliability and specificity ensure accurate and reproducible results in a variety of experimental settings. Whether investigating stem cell populations, immune cell subsets, or cancer cell phenotypes, this antibody opens up new possibilities for understanding the role of CD90 in health and disease.
Product Title:
APC Anti-Human CD90 Antibody [5E10]
SKU:
AGEL1830
Size:
20 Tests, 100 Tests, 200 Tests
Clone No:
5E10
Synonyms:
CDw90;T25;FLJ33325;Thy1;
Host Species:
Mouse
Reactivity:
Human
Application:
FCM
Isotype:
Mouse IgG1, κ
Isotype Control:
APC Mouse IgG1, κ Isotype Control[MOPC-21]
Form:
Liquid
Conjugation:
APC
Recommended Use:
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P04216
Gene ID:
7070
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD90 is a 25-35 kD GPI-anchored protein, also known as Thy-1. It belongs to the Ig superfamily. Human CD90 is expressed on neuronal cells, a subset of CD34+ cells, a subset of fetal liver cells and fetal thymocytes, fibroblasts, activated endothelial cells, and some leukemia cell lines. CD34+CD90+ cells are primitive hematopoietic stem cells. It has been reported that Thy-1 binds with β2 and β3 integrins and plays bimodal roles in the regulation of cell adhesion and neurite outgrowth, and inhibits hematopoietic stem cells proliferation and differentiation.