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PerCP Anti-Human CD8a Antibody [OKT-8] (AGEL0410)

SKU:
AGEL0410
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Host Species:
Mouse
Isotype:
IgG2a
Clone:
OKT-8
Conjugation:
PerCP
Applications:
FC
€139 - €469
Frequently bought together:

Description

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PerCP Anti-Human CD8a Antibody [OKT-8]

The Human CD8a Monoclonal Antibody (PERCP Conjugated, Clone OKT-8) is a vital tool for research involving the CD8a cell surface molecule, which serves as a marker for cytotoxic T cells. This antibody, derived from the OKT-8 clone, is optimized for flow cytometry applications and is highly specific to human CD8a samples, enabling accurate detection and analysis in various cell types.CD8a is a crucial component of the immune system, playing a key role in initiating immune responses and promoting cell-mediated immunity. Its expression on cytotoxic T cells helps in distinguishing them from other T cell subsets, making it an essential marker in immunology research, especially in studies related to infectious diseases, autoimmune disorders, and cancer.

The PERCP conjugation of this monoclonal antibody allows for easy integration into flow cytometry experiments, providing researchers with reliable and reproducible results. By targeting CD8a, this antibody facilitates the identification and characterization of cytotoxic T cells, aiding in the understanding of immune responses and contributing to advancements in immunotherapy and vaccine development.Overall, the Human CD8a Monoclonal Antibody (PERCP Conjugated, Clone OKT-8) from AssayGenie is a valuable tool for researchers looking to investigate the role of CD8a-expressing cells in immune function, disease pathogenesis, and therapeutic interventions.

Product Title:PerCP Anti-Human CD8a Antibody [OKT-8]
SKU:AGEL0410
Size:20 Tests, 100 Tests, 200 Tests
Clone No:OKT-8
Synonyms:T-cell surface glycoprotein CD8 alpha chain;CD8A;T-lymphocyte differentiation antigen T8/Leu-2;MAL;
Host Species:Mouse
Reactivity:Human
Application:FCM
Isotype:Mouse IgG2a, κ
Form:Liquid
Conjugation:PerCP
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P01732
Gene ID:925
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD8a is a 32-34 kD type I glycoprotein. It forms a homodimer (CD8a/a) or heterodimer (CD8a/b) with CD8b. CD8, also known as T8 and Leu2, is a member of the immunoglobulin superfamily found on the majority of thymocytes, a subset of peripheral blood T cells, and NK cells (which express almost exclusively CD8a homodimers). CD8 acts as a co-receptor with MHC class I-restricted T cell receptors in antigen recognition and T cell activation and has been shown to play a role in thymic differentiation. Two domains in CD8a are important for function: the extracellular IgSF domain binds the α3 domain of MHC class I and the cytoplasmic CXCP motif binds the tyrosine kinase p56 Lck.

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