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PE/Cyanine7 Anti-Human CD86 Antibody [BU63] (AGEL0648)

SKU:
AGEL0648
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Applications:
FC
$311 - $1,055
Frequently bought together:

Description

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PE/Cyanine7 Anti-Human CD86 Antibody [BU63]

The Human CD86 Monoclonal Antibody PE/Cyanine7 Conjugated (BU63) is a specialized tool for research focused on CD86, a key immune cell surface molecule with vital functions in immune response modulation. This monoclonal antibody, conjugated with PE/Cyanine7 for efficient detection, is highly specific for human samples and is optimized for flow cytometry applications.CD86, also known as B7-2, plays a crucial role in T cell activation and immune regulation by providing co-stimulatory signals necessary for effective immune responses. Its interactions with T cells and antigen-presenting cells influence the outcome of immune reactions, making it a significant target for studying various immune-related processes.

With its ability to accurately detect and quantify CD86 expression on different cell types, this monoclonal antibody facilitates detailed analysis of immune cell populations in research areas such as immunology, vaccine development, and autoimmune disease studies. By understanding the intricate functions of CD86, researchers can gain insights into immunological mechanisms and potentially discover novel therapeutic strategies for immune-related disorders.

Product Title:PE/Cyanine7 Anti-Human CD86 Antibody [BU63]
SKU:AGEL0648
Size:20 Tests, 100 Tests, 200 Tests
Clone No:BU63
Synonyms:T-lymphocyte activation antigen CD86;Cd86;Activation B7-2 antigen;Early T-cell costimulatory molecule 1;ETC-1;
Host Species:Mouse
Reactivity:Human
Application:FCM
Isotype:Mouse IgG1, κ
Isotype Control:PE/Cyanine7 Mouse IgG1, κ Isotype Control[MOPC-21]
Form:Liquid
Conjugation:PE/Cyanine 7
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P42081
Gene ID:942
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD86 is an 80 kD immunoglobulin superfamily member also known as B7-2, B70, and Ly-58. CD86 is expressed on activated B and T cells, monocytes/macrophages, dendritic cells, and astrocytes. CD86, along with CD80, is the ligand of CD28 and CD152 (CTLA-4). CD86 is expressed earlier in the immune response than CD80. CD86 has also been shown to be involved in immunoglobulin class-switching and triggering of NK cell-mediated cytotoxicity. CD86 binds to CD28 to transduce costimulatory signals for T cell activation, proliferation, and cytokine production. CD86 can bind to CD152 as well, also known as CTLA-4, to deliver an inhibitory signal to T cells.

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