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FITC Anti-Human CD86 Antibody [BU63] (AGEL0094)

SKU:
AGEL0094
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Host Species:
Mouse
Isotype:
IgG1
Clone:
BU63
Conjugation:
FITC
Applications:
FC
€189 - €629
Frequently bought together:

Description

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FITC Anti-Human CD86 Antibody [BU63]

The Human CD86 Monoclonal Antibody (FITC Conjugated) - BU63 (AGEL0094) is a valuable tool for researchers studying immune responses and cell signaling pathways. This monoclonal antibody specifically targets CD86, a crucial cell surface molecule involved in T cell activation and immune regulation.The antibody is conjugated with FITC, allowing for easy visualization and detection in various experimental assays. Its high specificity and sensitivity towards human CD86 make it a reliable reagent for flow cytometry, immunofluorescence, and other immunological techniques.CD86, also known as B7-2, is a co-stimulatory molecule that plays a pivotal role in the activation of T cells and the regulation of immune responses.

Understanding the expression and function of CD86 is essential for unraveling immune system dynamics in health and disease conditions such as infection, autoimmunity, and cancer.Researchers can leverage the Human CD86 Monoclonal Antibody (FITC Conjugated) - BU63 (AGEL0094) to investigate CD86 expression patterns, cell interactions, and immune modulation mechanisms, advancing our knowledge of immune system functionality and potentially guiding the development of novel therapeutic strategies.

Product Title:FITC Anti-Human CD86 Antibody [BU63]
SKU:AGEL0094
Size:20 Tests, 100 Tests, 200 Tests
Clone No:BU63
Synonyms:T-lymphocyte activation antigen CD86;Cd86;Activation B7-2 antigen;Early T-cell costimulatory molecule 1;ETC-1;
Host Species:Mouse
Reactivity:Human
Application:FCM
Isotype:Mouse IgG1, κ
Isotype Control:FITC Mouse IgG1, κ Isotype Control[MOPC-21]
Form:Liquid
Conjugation:FITC
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P42081
Gene ID:942
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD86 is an 80 kD immunoglobulin superfamily member also known as B7-2, B70, and Ly-58. CD86 is expressed on activated B and T cells, monocytes/macrophages, dendritic cells, and astrocytes. CD86, along with CD80, is the ligand of CD28 and CD152 (CTLA-4). CD86 is expressed earlier in the immune response than CD80. CD86 has also been shown to be involved in immunoglobulin class-switching and triggering of NK cell-mediated cytotoxicity. CD86 binds to CD28 to transduce costimulatory signals for T cell activation, proliferation, and cytokine production. CD86 can bind to CD152 as well, also known as CTLA-4, to deliver an inhibitory signal to T cells.

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