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Biotin Anti-Human CD86 Antibody [BU63] (AGEL0093)

SKU:
AGEL0093
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Host Species:
Mouse
Isotype:
IgG1
Clone:
BU63
Conjugation:
Biotin
Applications:
FC
€179 - €429
Frequently bought together:

Description

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Biotin Anti-Human CD86 Antibody [BU63]

The Human CD86 Monoclonal Antibody (BU63) is a vital tool for researchers investigating CD86, a crucial co-stimulatory molecule involved in immune activation and regulation. This monoclonal antibody, conjugated with biotin for versatile applications, specifically targets human CD86 and is suitable for various research techniques.CD86, also known as B7-2, is a key player in T cell activation and immune response modulation. Its interactions with T cells and antigen-presenting cells are essential for initiating and regulating adaptive immune responses. The CD86 Monoclonal Antibody (BU63) enables precise detection and analysis of CD86 expression in diverse cell types, facilitating detailed studies in immunology, vaccine development, and autoimmune disease research.

By utilizing this antibody, researchers can delve into the intricate mechanisms of immune regulation mediated by CD86, paving the way for insights into immune-related disorders and potential therapeutic strategies. The accurate detection and targeting of CD86 with this antibody offer valuable opportunities for advancing our understanding of immune system function and its implications in various pathological conditions.

Product Title:Biotin Anti-Human CD86 Antibody [BU63]
SKU:AGEL0093
Size:25µg, 100µg
Clone No:BU63
Synonyms:T-lymphocyte activation antigen CD86;Cd86;Activation B7-2 antigen;Early T-cell costimulatory molecule 1;ETC-1;
Host Species:Mouse
Reactivity:Human
Application:FCM
Isotype:Mouse IgG1, κ
Isotype Control:Biotin Mouse IgG1, κ Isotype Control[MOPC-21]
Form:Liquid
Conjugation:Biotin
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 µg per 106 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
Swissprot:P42081
Gene ID:942
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD86 is an 80 kD immunoglobulin superfamily member also known as B7-2, B70, and Ly-58. CD86 is expressed on activated B and T cells, monocytes/macrophages, dendritic cells, and astrocytes. CD86, along with CD80, is the ligand of CD28 and CD152 (CTLA-4). CD86 is expressed earlier in the immune response than CD80. CD86 has also been shown to be involved in immunoglobulin class-switching and triggering of NK cell-mediated cytotoxicity. CD86 binds to CD28 to transduce costimulatory signals for T cell activation, proliferation, and cytokine production. CD86 can bind to CD152 as well, also known as CTLA-4, to deliver an inhibitory signal to T cells.

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