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GenieFluor 488 Anti-Human CD86 Antibody [BU63] (AGEL0095)

SKU:
AGEL0095
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Host Species:
Mouse
Isotype:
IgG1
Clone:
BU63
Conjugation:
AF 488
Applications:
FC
€199 - €629
Frequently bought together:

Description

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GenieFluor 488 Anti-Human CD86 Antibody [BU63]

The Human CD86 Monoclonal Antibody (BU63) Alexa Fluor 488 Conjugated (AGEL0095) offered by Assay Genie is a cutting-edge tool for immunology research. Specifically targeting CD86, a crucial cell surface protein involved in immune activation, this antibody is meticulously designed for precision and accuracy in detecting CD86 expression in human samples. The Alexa Fluor 488 conjugation ensures high sensitivity and fluorescence intensity, making it ideal for flow cytometry and immunofluorescence applications.CD86, also known as B7-2, is a key co-stimulatory molecule that plays a pivotal role in T-cell activation and regulation of immune responses. By targeting CD86 with this monoclonal antibody, researchers can delve into the intricate mechanisms of immune signaling pathways, particularly in studies related to autoimmune diseases, transplant immunology, and infectious diseases.

The AGEL0095 antibody enables the visualization and quantification of CD86 expression, facilitating in-depth analysis of immune cell interactions and pathways.With its exceptional specificity and performance in experimental settings, the Human CD86 Monoclonal Antibody (BU63) Alexa Fluor 488 Conjugated (AGEL0095) from Assay Genie is an invaluable asset for advancing scientific discoveries in immunology and biomedicine. Unlock new insights into immune regulation and host-pathogen interactions with this state-of-the-art research tool.

Product Title:GenieFluor 488 Anti-Human CD86 Antibody [BU63]
SKU:AGEL0095
Size:20 Tests, 100 Tests, 200 Tests
Clone No:BU63
Synonyms:T-lymphocyte activation antigen CD86;Cd86;Activation B7-2 antigen;Early T-cell costimulatory molecule 1;ETC-1;
Host Species:Mouse
Reactivity:Human
Application:FCM
Isotype:Mouse IgG1, κ
Isotype Control:Genie Fluor 488 Mouse IgG1, κ Isotype Control[MOPC-21]
Form:Liquid
Conjugation:Genie Fluor488
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P42081
Gene ID:942
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD86 is an 80 kD immunoglobulin superfamily member also known as B7-2, B70, and Ly-58. CD86 is expressed on activated B and T cells, monocytes/macrophages, dendritic cells, and astrocytes. CD86, along with CD80, is the ligand of CD28 and CD152 (CTLA-4). CD86 is expressed earlier in the immune response than CD80. CD86 has also been shown to be involved in immunoglobulin class-switching and triggering of NK cell-mediated cytotoxicity. CD86 binds to CD28 to transduce costimulatory signals for T cell activation, proliferation, and cytokine production. CD86 can bind to CD152 as well, also known as CTLA-4, to deliver an inhibitory signal to T cells.

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