The Human CD83 Monoclonal Antibody PE-conjugated (HB15e) is a powerful tool for researchers studying immune cells and their functions. CD83 is a cell surface protein that plays a key role in the activation and maturation of immune cells, particularly dendritic cells.This monoclonal antibody, labeled with PE for convenient detection in flow cytometry and immunofluorescence studies, specifically targets CD83 protein in human samples. By binding to CD83, this antibody allows for the precise identification and analysis of dendritic cells, as well as other immune cell subsets expressing CD83.Studying CD83 is essential for unraveling the intricacies of immune responses, such as antigen presentation and T cell activation, which are crucial for mounting effective immune defenses against pathogens and cancer cells.
This antibody provides a reliable tool for investigating the role of CD83 in various immunological processes, making it invaluable for research in immunology, vaccine development, and autoimmune diseases.With its high specificity and sensitivity, the Human CD83 Monoclonal Antibody PE-conjugated (HB15e) enables researchers to delve deeper into the complex interactions of immune cells and paves the way for new discoveries in the field of immunology.
Product Title:
PE Anti-Human CD83 Antibody [HB15e]
SKU:
AGEL0542
Size:
20 Tests, 100 Tests, 200 Tests
Clone No:
HB15e
Synonyms:
BL11;CD83;HB15;
Host Species:
Mouse
Reactivity:
Human
Application:
FCM
Isotype:
Mouse IgG1, κ
Isotype Control:
PE Mouse IgG1, κ Isotype Control[MOPC-21]
Form:
Liquid
Conjugation:
PE
Recommended Use:
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
Q01151
Gene ID:
9311
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD83 is a 43 kD single chain type I glycoprotein also known as HB15. A member of the immunoglobulin superfamily, CD83 is expressed on a subset of dendritic cells, Langerhans cells, and weakly on activated lymphocytes. Although CD83 is thought to play a role in antigen presentation and/or lymphocyte activation, the precise function of this protein is unknown. CD83 is considered to be a useful marker for mature dendritic cells.