The Human CD83 Monoclonal Antibody (APC Conjugated, clone HB15e) is a powerful tool for researchers investigating the CD83 protein, a key marker of dendritic cell maturation and activation. This monoclonal antibody, produced using the HB15e hybridoma cell line, is specifically conjugated with APC for enhanced detection in flow cytometry applications. With high specificity for human CD83, this antibody offers reliable and accurate analysis of dendritic cell populations in various biological samples.CD83 is a transmembrane glycoprotein that plays a critical role in immune responses, particularly in the regulation of T cell activation and tolerance. Its expression on dendritic cells is indicative of their maturation and antigen-presenting capacity, making CD83 a valuable target for studies in immunology and vaccine development.
By targeting CD83 with this monoclonal antibody, researchers can gain insights into dendritic cell function, immune regulation, and potential applications in immunotherapy.Overall, the Human CD83 Monoclonal Antibody (APC Conjugated, clone HB15e) offers researchers a reliable tool for investigating dendritic cell biology, immune responses, and therapeutic strategies in various disease contexts. Its specificity and conjugation with APC make it a valuable resource for advancing our understanding of CD83-mediated immune modulation and its implications for health and disease.
Product Title:
APC Anti-Human CD83 Antibody [HB15e]
SKU:
AGEL0543
Size:
20 Tests, 100 Tests, 200 Tests
Clone No:
HB15e
Synonyms:
BL11;CD83;HB15;
Host Species:
Mouse
Reactivity:
Human
Application:
FCM
Isotype:
Mouse IgG1, κ
Isotype Control:
APC Mouse IgG1, κ Isotype Control[MOPC-21]
Form:
Liquid
Conjugation:
APC
Recommended Use:
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
Q01151
Gene ID:
9312
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD83 is a 43 kD single chain type I glycoprotein also known as HB15. A member of the immunoglobulin superfamily, CD83 is expressed on a subset of dendritic cells, Langerhans cells, and weakly on activated lymphocytes. Although CD83 is thought to play a role in antigen presentation and/or lymphocyte activation, the precise function of this protein is unknown. CD83 is considered to be a useful marker for mature dendritic cells.