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Human CD80 Recombinant Protein (His tag)

SKU:
RPES6079
Product Type:
Recombinant Protein
Species:
Human
€429
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Description

Product Name:Human CD80 Recombinant Protein (His tag)
Product Code:RPES6079
Size:20µg
Species:Human
Expression Host:HEK293 Cells
Synonyms:CD80, Activation B7-1 antigen, B7, BB1, CD28LG1, CD28LGB7-1 antigen, T-lymphocyte activation antigen CD80, B7-1, B7.1, CD28LG, LAB7
Mol Mass:26.51 kDa
AP Mol Mass:40 kDa
Tag:C-His
Purity:> 95 % as determined by reducing SDS-PAGE.
Endotoxin Level:Please contact us for more information.
Bio Activity:Testing in progress
Sequence:Met1-Asn242
Accession:P33681
Storage:Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Shipping:This product is provided as lyophilized powder which is shipped with ice packs.
Formulation:Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual.
Reconstitution:Please refer to the printed manual for detailed information.
Background:Cluster of Differentiation 80; also called B7-1; is a member of cell surface immunoglobulin superfamily which plays key; yet distinct roles in the activation of T cells. It is the ligand for two different proteins on the T cell surface: CD28 and CTLA-4. Studies have shown that CTLA-4 binds mostly to CD80. The structure presents two extracellular domains: a membrane distal variable-like domain (IgV) and a membrane proximal Ig constant-like domain (IgC) along with an intracellular domain. Both IgV and IgC consist of anti-parallel beta sandwiches joined by a short linker region. CD80 is mostly expressed on the surface of antigen-presenting cells including activated B cells; macrophages and dendritic cells.

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