Human CD72 Recombinant Protein (RPPB3089)
- SKU:
- RPPB3089
- Product Type:
- Recombinant Protein
- Species:
- Human
- Uniprot:
- P21854
- Research Area:
- CD Antigens
Description
| Product Name: | Human CD72 Recombinant Protein |
| Product Code: | RPPB3089 |
| Size: | 5µg |
| Species: | Human |
| Target: | CD72 |
| Synonyms: | B-cell differentiation antigen CD72, Lyb-2, CD72, LYB2, CD72b. |
| Source: | Escherichia Coli |
| Physical Appearance: | Sterile Filtered clear solution. |
| Formulation: | CD72 at 100�g/ml in 50mM Tris-HCl, pH7.5, 10mM L-glutathione (reduced). |
| Stability: | Store vial at -20°C to -80°C. When stored at the recommended temperature, this protein is stable for 12 months.Please prevent freeze-thaw cycles. |
CD72 antigen is a member of the type II integral membrane glycoproteins which includes other related cell surface moleculaes such as the asialoglycoprotein receptors, CD23 and the Kupffer cell recpeotr. The function of CD72 is unknown but the exposure of B cells to CD72 antibodies activates a variety of signaling pathways and can induce MHC class II expression and B cell proliferation. CD72 antigen is expressed on all cells of B cell lineage with the exception of plasma cells and weakly on human tissue macrophages.
CD72 Human Recombinant (aa 1-98) expressed in E.coli, shows a 38 kDa band on SDS-PAGE. The CD72 is purified by proprietary chromatographic techniques.
| UniProt Protein Function: | CD72: Plays a role in B-cell proliferation and differentiation. |
| UniProt Protein Details: | Protein type:Cell adhesion; Membrane protein, integral Chromosomal Location of Human Ortholog: 9p13.3 Cellular Component: integral to plasma membrane; plasma membrane Molecular Function:protein binding; receptor binding Biological Process: cell adhesion |
| UniProt Code: | P21854 |
| NCBI GenInfo Identifier: | 116029 |
| NCBI Gene ID: | 971 |
| NCBI Accession: | P21854.1 |
| UniProt Related Accession: | P21854 |
| Molecular Weight: | 40,220 Da |
| NCBI Full Name: | B-cell differentiation antigen CD72 |
| NCBI Synonym Full Names: | CD72 molecule |
| NCBI Official Symbol: | CD72�� |
| NCBI Official Synonym Symbols: | LYB2; CD72b�� |
| NCBI Protein Information: | B-cell differentiation antigen CD72 |
| UniProt Protein Name: | B-cell differentiation antigen CD72 |
| UniProt Synonym Protein Names: | Lyb-2; CD_antigen: CD72 |
| Protein Family: | B-cell differentiation antigen |
| UniProt Gene Name: | CD72�� |
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