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PE/Cyanine5 Anti-Human CD69 Antibody [FN50] (AGEL1690)

SKU:
AGEL1690
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Applications:
FC
€219 - €469
Frequently bought together:

Description

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PE/Cyanine5 Anti-Human CD69 Antibody [FN50]

The Human CD69 Monoclonal Antibody PE-Cyanine5 Conjugated (FN50) is a specialized tool designed for scientists investigating CD69, a key marker of early lymphocyte activation and a crucial player in immune response regulation. This monoclonal antibody, conjugated with PE-Cyanine5, offers high specificity and sensitivity for detecting CD69 in human samples, making it an invaluable resource for flow cytometry and immunofluorescence studies.CD69, also known as very early activation antigen, is rapidly induced on the surface of lymphocytes upon activation, serving as a reliable indicator of immune cell stimulation. By targeting CD69 with this conjugated monoclonal antibody, researchers can precisely identify and analyze activated lymphocytes in diverse experimental settings, including immunology, infectious diseases, and inflammatory disorders.

The functionality of CD69 in initiating immune responses and influencing immune cell interactions underscores its significance in understanding immune system dynamics and developing targeted therapies. By utilizing the Human CD69 Monoclonal Antibody PE-Cyanine5 Conjugated (FN50), researchers can delve deeper into the mechanisms of immune activation and modulation, paving the way for advancements in immunotherapy, vaccine development, and autoimmune disease research.

Product Title:PE/Cyanine5 Anti-Human CD69 Antibody [FN50]
SKU:AGEL1690
Size:20 Tests, 100 Tests, 200 Tests
Clone No:FN50
Synonyms:Early activation antigen CD69;Activation inducer molecule;AIM;EA1;MLR-3;
Host Species:Mouse
Reactivity:Human
Application:FCM
Isotype:Mouse IgG1, κ
Form:Liquid
Conjugation:PE/Cyanine 5
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:Q07108
Gene ID:969
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD69 is a 27-33 kD type II transmembrane protein also known as activation inducer molecule (AIM), very early activation antigen (VEA), and MLR3. It is a member of the C-type lectin family, expressed as a disulfide-linked homodimer. Other members of this receptor family include NKG2, NKR-P1 CD94, and Ly49. CD69 is transiently expressed on activated leukocytes including T cells, thymocytes, B cells, NK cells, neutrophils, and eosinophils. CD69 is constitutively expressed by a subset of medullary mature thymocytes, platelets, mantle B cells, and certain CD4+ T cells in germinal centers of normal lymph nodes. CD69 is involved in early events of lymphocyte, monocyte, and platelet activation, and has a functional role in redirected lysis mediated by activated NK cells.

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