The Human CD69 Monoclonal Antibody (AF647 Conjugated, Clone FN50) is a cutting-edge tool for research involving CD69, a transmembrane protein known for its role in immune activation and lymphocyte proliferation. This antibody, conjugated with AF647 for fluorescence-based applications, has been developed and validated by Assay Genie for use in flow cytometry and immunofluorescence assays.CD69 is a crucial marker of early activation of T cells, NK cells, and other immune cells, indicating their responsiveness to various stimuli. The CD69 Monoclonal Antibody enables precise and sensitive detection of CD69 expression on cell surfaces, aiding in the identification and characterization of activated immune cells in different experimental settings.
With its high specificity and sensitivity, this antibody is an essential tool for researchers investigating immune responses, inflammation, and cell signaling pathways. By targeting CD69, researchers can further explore its functions in immune regulation, infection, autoimmunity, and cancer immunity. The robust performance of this antibody makes it an invaluable asset for studies aiming to unravel the complexities of immune activation and its implications in various biological processes.
Product Title:
GenieFluor 647 Anti-Human CD69 Antibody [FN50]
SKU:
AGEL1695
Size:
20 Tests, 100 Tests, 200 Tests
Clone No:
FN50
Synonyms:
Early activation antigen CD69;Activation inducer molecule;AIM;EA1;MLR-5;
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
Q07108
Gene ID:
969
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD69 is a 27-33 kD type II transmembrane protein also known as activation inducer molecule (AIM), very early activation antigen (VEA), and MLR3. It is a member of the C-type lectin family, expressed as a disulfide-linked homodimer. Other members of this receptor family include NKG2, NKR-P1 CD94, and Ly49. CD69 is transiently expressed on activated leukocytes including T cells, thymocytes, B cells, NK cells, neutrophils, and eosinophils. CD69 is constitutively expressed by a subset of medullary mature thymocytes, platelets, mantle B cells, and certain CD4+ T cells in germinal centers of normal lymph nodes. CD69 is involved in early events of lymphocyte, monocyte, and platelet activation, and has a functional role in redirected lysis mediated by activated NK cells.