The Human CD69 Monoclonal Antibody (AF488 Conjugated) (FN50) is an essential tool for researchers studying CD69, a key marker of lymphocyte activation and tissue residency. This monoclonal antibody, conjugated with AF488 for fluorescent detection, provides high specificity and sensitivity in identifying CD69-expressing cells in human samples.CD69 is a transmembrane protein expressed on the surface of activated lymphocytes and is involved in regulating immune responses. Its rapid upregulation upon activation makes it a valuable indicator of immune cell activation in various contexts, such as infection, inflammation, and autoimmunity. The AF488-conjugated CD69 antibody enables precise visualization and quantification of CD69 expression in flow cytometry, immunofluorescence, and other techniques, facilitating detailed analysis of immune cell activation and migration patterns.
Researchers in immunology, infectious diseases, and autoimmunity can benefit from the use of the Human CD69 Monoclonal Antibody (AF488 Conjugated) (FN50) to deepen their understanding of immune responses and cell dynamics in health and disease. By accurately detecting and characterizing CD69-expressing cells, this antibody opens up avenues for investigating immune activation mechanisms and developing targeted therapies for a range of conditions.
Product Title:
GenieFluor 488 Anti-Human CD69 Antibody [FN50]
SKU:
AGEL1694
Size:
20 Tests, 100 Tests, 200 Tests
Clone No:
FN50
Synonyms:
Early activation antigen CD69;Activation inducer molecule;AIM;EA1;MLR-4;
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
Q07108
Gene ID:
969
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD69 is a 27-33 kD type II transmembrane protein also known as activation inducer molecule (AIM), very early activation antigen (VEA), and MLR3. It is a member of the C-type lectin family, expressed as a disulfide-linked homodimer. Other members of this receptor family include NKG2, NKR-P1 CD94, and Ly49. CD69 is transiently expressed on activated leukocytes including T cells, thymocytes, B cells, NK cells, neutrophils, and eosinophils. CD69 is constitutively expressed by a subset of medullary mature thymocytes, platelets, mantle B cells, and certain CD4+ T cells in germinal centers of normal lymph nodes. CD69 is involved in early events of lymphocyte, monocyte, and platelet activation, and has a functional role in redirected lysis mediated by activated NK cells.