The Human CD64 Monoclonal Antibody (FITC-conjugated, 10-1) offered by AssayGenie (product code: AGEL0314) is a cutting-edge tool for research applications involving CD64, a key cell surface receptor widely studied in immunology. This monoclonal antibody, conjugated with FITC for fluorescence detection, is well-suited for use in flow cytometry and other immunofluorescence-based assays.The CD64 receptor, also known as FcγRI, plays a crucial role in mediating immune responses by binding to the Fc portion of immunoglobulins, particularly IgG. Its expression is primarily found on cells of the innate immune system such as monocytes, macrophages, and neutrophils. The CD64 Monoclonal Antibody specifically targets this receptor, enabling precise detection and characterization of CD64-expressing cells in various biological samples.
With its high specificity and sensitivity, this antibody is an invaluable asset for researchers delving into immune system function, inflammatory responses, and antibody-mediated pathways. The FITC conjugation enhances visualization and quantification of CD64-expressing cells, facilitating detailed analyses in the fields of immunology, infection, autoimmunity, and inflammation. In conclusion, the Human CD64 Monoclonal Antibody (FITC-conjugated, 10-1) from AssayGenie provides a reliable and efficient tool for investigating CD64 biology and function, opening up new avenues for understanding immune processes and potentially identifying therapeutic targets in various disease contexts.
Product Title:
FITC Anti-Human CD64 Antibody [10.1]
SKU:
AGEL0314
Size:
20 Tests, 100 Tests, 200 Tests
Clone No:
10.1
Synonyms:
Fc fragment of IgG high affinity Ia/b/c receptor;CD64A/B/C;CD64;Fc gamma RI;FCGR1A/B/C;IGFR 1;
Host Species:
Mouse
Reactivity:
Human
Application:
FCM
Isotype:
Mouse IgG1, κ
Isotype Control:
FITC Mouse IgG1, κ Isotype Control[MOPC-21]
Form:
Liquid
Conjugation:
FITC
Recommended Use:
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P12314
Gene ID:
2209
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD64 is a 72 kD single chain type I glycoprotein also known as FcγRI and FcR I. CD64 is a member of the immunoglobulin superfamily and is expressed on monocytes/macrophages, dendritic cells, and activated granulocytes. The expression can be upregulated by IFN-γ stimulation. CD64 binds IgG immune complex. It plays a role in antigen capture, phagocytosis of IgG/antigen complexes, and antibody-dependent cellular cytotoxicity (ADCC).