The Human CD64 Monoclonal Antibody (Biotin Conjugated, 10-1) is a cutting-edge tool designed for precise research applications involving the CD64 protein, a key cell surface receptor involved in immune responses. This antibody, manufactured to the highest standards, exhibits exceptional reactivity with human samples and is optimized for a variety of experimental techniques, including immunofluorescence and flow cytometry.CD64, also known as FcγRI, plays a pivotal role in immune signaling and phagocytosis, particularly in the context of immunoglobulin-mediated responses. Its expression on various immune cells makes it a crucial target for investigating immune activation, pathogen recognition, and inflammatory processes.
By utilizing this specialized antibody, researchers gain a powerful tool for investigating the functions and regulatory mechanisms of CD64 in diverse physiological and pathological conditions, such as infectious diseases, autoimmune disorders, and immunotherapy development.For laboratories engaged in immunology, cellular biology, or therapeutic research, the Human CD64 Monoclonal Antibody offers a versatile and reliable solution for unraveling the complexities of immune signaling pathways and exploring novel therapeutic strategies. Unlock the potential of CD64 research with this high-quality antibody, ideal for advancing our understanding of immune responses and paving the way for innovative medical interventions.
Product Title:
Biotin Anti-Human CD64 Antibody [10.1]
SKU:
AGEL0313
Size:
25µg, 100µg
Clone No:
10.1
Synonyms:
Fc fragment of IgG high affinity Ia/b/c receptor;CD64A/B/C;CD64;Fc gamma RI;FCGR1A/B/C;IGFR 1;
Host Species:
Mouse
Reactivity:
Human
Application:
FCM
Isotype:
Mouse IgG1, κ
Isotype Control:
Biotin Mouse IgG1, κ Isotype Control[MOPC-21]
Form:
Liquid
Conjugation:
Biotin
Recommended Use:
Each lot of this antibody is quality control tested by flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 µg per 106 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
Swissprot:
P12314
Gene ID:
2209
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD64 is a 72 kD single chain type I glycoprotein also known as FcγRI and FcR I. CD64 is a member of the immunoglobulin superfamily and is expressed on monocytes/macrophages, dendritic cells, and activated granulocytes. The expression can be upregulated by IFN-γ stimulation. CD64 binds IgG immune complex. It plays a role in antigen capture, phagocytosis of IgG/antigen complexes, and antibody-dependent cellular cytotoxicity (ADCC).