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PerCP/Cyanine5.5 Anti-Human CD62L Antibody [DREG56] (AGEL0954)

SKU:
AGEL0954
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Applications:
FC
$299 - $719
Frequently bought together:

Description

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PerCP/Cyanine5.5 Anti-Human CD62L Antibody [DREG56]

The Human CD62L Monoclonal Antibody (PERCP-Cyanine5.5 Conjugated) - clone DREG56 (AGEL0954) is a powerful tool for immunology research, specifically targeting CD62L, a cell surface molecule involved in leukocyte migration and adhesion. This antibody, derived from a monoclonal source, is optimized for use in flow cytometry applications and is extensively validated for high specificity and sensitivity in detecting CD62L expression on human samples.CD62L, also known as L-selectin, plays a crucial role in the recruitment of immune cells to sites of inflammation and in lymphocyte homing to secondary lymphoid organs. Its involvement in immune cell trafficking makes it a key player in immune responses, making the CD62L Monoclonal Antibody an essential tool for investigating immune cell function and understanding the mechanisms behind immune system regulation.

By utilizing the CD62L Monoclonal Antibody in your research, you can gain insights into the role of CD62L in various immune processes, including leukocyte adhesion, migration, and homing, providing valuable information for studies related to inflammation, infection, and autoimmune diseases. With its high specificity and exceptional performance in flow cytometry, this antibody is an excellent choice for researchers looking to explore the intricate functions of CD62L in immunology and beyond.

Product Title:PerCP/Cyanine5.5 Anti-Human CD62L Antibody [DREG56]
SKU:AGEL0954
Size:20 Tests, 100 Tests, 200 Tests
Clone No:DREG56
Synonyms:L-selectin;Sell;CD62 antigen-like family member L;LAM-1;LECAM1;Lymph node homing receptor;Ly-22; CD62L;Lnhr;Ly22;
Host Species:Mouse
Reactivity:Human
Application:FCM
Isotype:Mouse IgG1, κ
Isotype Control:PerCP/Cyanine5.5 Mouse IgG1, κ Isotype Control[MOPC-21]
Form:Liquid
Conjugation:PerCP/Cyanine 5.5
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P14151
Gene ID:6402
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD62L is a 74-95 kD single chain type I glycoprotein referred to as L-selectin or LECAM-1. It is expressed on most peripheral blood B cells, subsets of T and NK cells, monocytes, granulocytes, and certain hematopoietic malignant cells. CD62L binds to carbohydrates present on certain glycoforms of CD34, glycam-1, and MAdCAM-1 and with a low affinity to anionic oligosaccharide sequences related to sialylated Lewis X (sLex, CD15s) through its C-type lectin domain. CD62L is important for the homing of naïve lymphocytes to high endothelial venules in peripheral lymph nodes and Peyer's patches. It also plays a role in leukocyte rolling on activated endothelial cells.

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