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PE/Cyanine5 Anti-Human CD62L Antibody [DREG56] (AGEL0951)

SKU:
AGEL0951
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Applications:
FC
€139 - €469
Frequently bought together:

Description

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PE/Cyanine5 Anti-Human CD62L Antibody [DREG56]

The CD62L Monoclonal Antibody (PE-Cyanine5 Conjugated) (DREG56) is a powerful tool for researchers studying immune cell activation and migration. This antibody, specifically designed for use in flow cytometry applications, targets the CD62L protein, which is a key adhesion molecule involved in the homing of lymphocytes to secondary lymphoid organs.CD62L, also known as L-selectin, plays a crucial role in the immune response by facilitating the interaction between circulating immune cells and endothelial cells. By binding to CD62L, the DREG56 antibody allows for the detection and analysis of lymphocyte populations expressing this important marker. It is highly specific to human samples, ensuring accurate results in research focused on immune cell trafficking and immune system function.

With its PE-Cyanine5 conjugation, this antibody provides robust and reliable fluorescence detection, making it an essential tool for immunologists and researchers studying inflammatory responses, infectious diseases, and immune cell activation. By targeting CD62L, this antibody aids in understanding the mechanisms underlying immune cell recruitment and activation, opening up avenues for exploring therapeutic strategies in conditions such as autoimmune diseases, infections, and inflammation-related disorders.

Product Title:PE/Cyanine5 Anti-Human CD62L Antibody [DREG56]
SKU:AGEL0951
Size:20 Tests, 100 Tests, 200 Tests
Clone No:DREG56
Synonyms:L-selectin;Sell;CD62 antigen-like family member L;LAM-1;LECAM1;Lymph node homing receptor;Ly-22; CD62L;Lnhr;Ly22;
Host Species:Mouse
Reactivity:Human
Application:FCM
Isotype:Mouse IgG1, κ
Form:Liquid
Conjugation:PE/Cyanine 5
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P14151
Gene ID:6402
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD62L is a 74-95 kD single chain type I glycoprotein referred to as L-selectin or LECAM-1. It is expressed on most peripheral blood B cells, subsets of T and NK cells, monocytes, granulocytes, and certain hematopoietic malignant cells. CD62L binds to carbohydrates present on certain glycoforms of CD34, glycam-1, and MAdCAM-1 and with a low affinity to anionic oligosaccharide sequences related to sialylated Lewis X (sLex, CD15s) through its C-type lectin domain. CD62L is important for the homing of naïve lymphocytes to high endothelial venules in peripheral lymph nodes and Peyer's patches. It also plays a role in leukocyte rolling on activated endothelial cells.

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