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FITC Anti-Human CD62L Antibody [DREG56] (AGEL0224)

SKU:
AGEL0224
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Host Species:
Mouse
Isotype:
IgG1
Clone:
DREG56
Conjugation:
FITC
Applications:
FC
$131 - $419
Frequently bought together:

Description

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FITC Anti-Human CD62L Antibody [DREG56]

The Human CD62L Monoclonal Antibody (FITC-conjugated) DREG56 (AGEL0224) is a powerful tool for researchers studying immune cell adhesion molecules and their role in inflammatory responses. This antibody specifically targets CD62L, a key marker for lymphocyte homing to peripheral lymph nodes and sites of inflammation. By binding to CD62L, this monoclonal antibody enables precise detection and analysis of immune cell populations expressing this important adhesion molecule.CD62L, also known as L-selectin, plays a critical role in the immune response by facilitating the migration of lymphocytes to sites of infection and inflammation. It is involved in the initial steps of immune cell extravasation from the blood into peripheral tissues, making it a key player in the inflammatory cascade.

By targeting CD62L with this monoclonal antibody, researchers can gain valuable insights into the mechanisms underlying immune cell trafficking and activation.This FITC-conjugated monoclonal antibody offers high specificity and sensitivity for CD62L detection, making it suitable for a wide range of research applications including flow cytometry, immunofluorescence, and cell sorting. Its compatibility with human samples ensures reliable and accurate results for studies focused on immune cell behavior and function. Researchers in immunology, inflammation, and infectious disease fields will find this antibody to be an indispensable tool for advancing their research goals and understanding immune cell dynamics in health and disease.

Product Title:FITC Anti-Human CD62L Antibody [DREG56]
SKU:AGEL0224
Size:20 Tests, 100 Tests, 200 Tests
Clone No:DREG56
Synonyms:L-selectin;Sell;CD62 antigen-like family member L;LAM-1;LECAM1;Lymph node homing receptor;Ly-22; CD62L;Lnhr;Ly22;
Host Species:Mouse
Reactivity:Human
Application:FCM
Isotype:Mouse IgG1, κ
Isotype Control:FITC Mouse IgG1, κ Isotype Control[MOPC-21]
Form:Liquid
Conjugation:FITC
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P14151
Gene ID:6402
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD62L is a 74-95 kD single chain type I glycoprotein referred to as L-selectin or LECAM-1. It is expressed on most peripheral blood B cells, subsets of T and NK cells, monocytes, granulocytes, and certain hematopoietic malignant cells. CD62L binds to carbohydrates present on certain glycoforms of CD34, glycam-1, and MAdCAM-1 and with a low affinity to anionic oligosaccharide sequences related to sialylated Lewis X (sLex, CD15s) through its C-type lectin domain. CD62L is important for the homing of naïve lymphocytes to high endothelial venules in peripheral lymph nodes and Peyer's patches. It also plays a role in leukocyte rolling on activated endothelial cells.

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