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Biotin Anti-Human CD62L Antibody [DREG56] (AGEL0223)

SKU:
AGEL0223
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Host Species:
Mouse
Isotype:
IgG1
Clone:
DREG56
Conjugation:
Biotin
Applications:
FC
€129 - €329
Frequently bought together:

Description

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Biotin Anti-Human CD62L Antibody [DREG56]

The Human CD62L Monoclonal Antibody (Biotin Conjugated) - DREG56 (AGEL0223) offered by AssayGenie is a valuable tool for researchers studying CD62L, a cell adhesion molecule essential for immune cell trafficking. This monoclonal antibody, conjugated with biotin, is specifically designed for use in various applications, such as flow cytometry and immunohistochemistry, to detect and analyze CD62L expression in human samples.CD62L, also known as L-selectin, plays a crucial role in the migration of immune cells to sites of inflammation and infection. By targeting CD62L, researchers can gain insights into the mechanisms underlying immune cell recruitment and activation, making this antibody a valuable asset for studies in immunology, inflammation, and infectious diseases.

With its high specificity and sensitivity, the Human CD62L Monoclonal Antibody (Biotin Conjugated) - DREG56 (AGEL0223) from AssayGenie enables precise detection of CD62L in various cell types and tissues, providing researchers with reliable data for their experiments. Explore the functions and regulation of CD62L with this high-quality antibody, advancing your research in immunology and beyond.

Product Title:Biotin Anti-Human CD62L Antibody [DREG56]
SKU:AGEL0223
Size:25µg, 100µg
Clone No:DREG56
Synonyms:L-selectin;Sell;CD62 antigen-like family member L;LAM-1;LECAM1;Lymph node homing receptor;Ly-22; CD62L;Lnhr;Ly22;
Host Species:Mouse
Reactivity:Human
Application:FCM
Isotype:Mouse IgG1, κ
Isotype Control:Biotin Mouse IgG1, κ Isotype Control[MOPC-21]
Form:Liquid
Conjugation:Biotin
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 µg per 106 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
Swissprot:P14151
Gene ID:6402
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD62L is a 74-95 kD single chain type I glycoprotein referred to as L-selectin or LECAM-1. It is expressed on most peripheral blood B cells, subsets of T and NK cells, monocytes, granulocytes, and certain hematopoietic malignant cells. CD62L binds to carbohydrates present on certain glycoforms of CD34, glycam-1, and MAdCAM-1 and with a low affinity to anionic oligosaccharide sequences related to sialylated Lewis X (sLex, CD15s) through its C-type lectin domain. CD62L is important for the homing of naïve lymphocytes to high endothelial venules in peripheral lymph nodes and Peyer's patches. It also plays a role in leukocyte rolling on activated endothelial cells.

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