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APC Anti-Human CD62L Antibody [DREG56] (AGEL0225)

SKU:
AGEL0225
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Host Species:
Mouse
Isotype:
IgG1
Clone:
DREG56
Conjugation:
APC
Applications:
FC
€239 - €519
Frequently bought together:

Description

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APC Anti-Human CD62L Antibody [DREG56]

The Human CD62L Monoclonal Antibody (APC-conjugated) is a cutting-edge tool for researchers studying CD62L, a key cell surface marker involved in immune cell trafficking and activation. This monoclonal antibody, clone DREG56, is specifically designed for use in flow cytometry applications, providing accurate and reliable detection of CD62L expression in human samples.CD62L, also known as L-selectin, plays a vital role in the adhesion and migration of immune cells, particularly in the lymphoid system. Its expression levels can indicate the activation status of T cells and are crucial for understanding immune responses in various physiological and pathological conditions.

The APC-conjugated DREG56 antibody offers high specificity and sensitivity, allowing for detailed analysis of CD62L-expressing cells in diverse experimental settings.Researchers in immunology, inflammation, and infectious diseases will find the Human CD62L Monoclonal Antibody (APC-conjugated) a valuable tool for investigating lymphocyte trafficking, immune cell activation, and inflammatory processes. With its reliable performance and broad applicability, this antibody supports in-depth exploration of CD62L biology and its implications in immune function and disease pathogenesis.

Product Title:APC Anti-Human CD62L Antibody [DREG56]
SKU:AGEL0225
Size:20 Tests, 100 Tests, 200 Tests
Clone No:DREG56
Synonyms:L-selectin;Sell;CD62 antigen-like family member L;LAM-1;LECAM1;Lymph node homing receptor;Ly-22; CD62L;Lnhr;Ly22;
Host Species:Mouse
Reactivity:Human
Application:FCM
Isotype:Mouse IgG1, κ
Isotype Control:APC Mouse IgG1, κ Isotype Control[MOPC-21]
Form:Liquid
Conjugation:APC
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P14151
Gene ID:6402
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD62L is a 74-95 kD single chain type I glycoprotein referred to as L-selectin or LECAM-1. It is expressed on most peripheral blood B cells, subsets of T and NK cells, monocytes, granulocytes, and certain hematopoietic malignant cells. CD62L binds to carbohydrates present on certain glycoforms of CD34, glycam-1, and MAdCAM-1 and with a low affinity to anionic oligosaccharide sequences related to sialylated Lewis X (sLex, CD15s) through its C-type lectin domain. CD62L is important for the homing of naïve lymphocytes to high endothelial venules in peripheral lymph nodes and Peyer's patches. It also plays a role in leukocyte rolling on activated endothelial cells.

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