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GenieFluor 488 Anti-Human CD62L Antibody [DREG56] (AGEL0226)

SKU:
AGEL0226
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Host Species:
Mouse
Isotype:
IgG1
Clone:
DREG56
Conjugation:
AF 488
Applications:
FC
€139 - €469
Frequently bought together:

Description

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GenieFluor 488 Anti-Human CD62L Antibody [DREG56]

The Human CD62L Monoclonal Antibody (Alexa Fluor 488 Conjugated) DREG56 (AGEL0226) is a cutting-edge tool for researchers studying the CD62L molecule, a key player in immune cell trafficking and activation. This monoclonal antibody, designed for use with human samples, is conjugated with Alexa Fluor 488 for enhanced detection and visualization capabilities.CD62L, also known as L-selectin, is a cell adhesion molecule crucial for lymphocyte homing and migration to secondary lymphoid organs. Its expression on the surface of immune cells facilitates their interaction with high endothelial venules, enabling proper immune responses.

The DREG56 antibody specifically targets CD62L, allowing for precise identification and analysis in a variety of experimental settings.Researchers in immunology, cancer biology, and infectious diseases will find the Human CD62L Monoclonal Antibody (Alexa Fluor 488 Conjugated) DREG56 (AGEL0226) invaluable for investigating immune cell behavior, inflammation, and immune surveillance mechanisms. With its high specificity and sensitivity, this antibody is a valuable asset for elucidating the role of CD62L in diverse physiological and pathological processes.

Product Title:GenieFluor 488 Anti-Human CD62L Antibody [DREG56]
SKU:AGEL0226
Size:20 Tests, 100 Tests, 200 Tests
Clone No:DREG56
Synonyms:L-selectin;Sell;CD62 antigen-like family member L;LAM-1;LECAM1;Lymph node homing receptor;Ly-22; CD62L;Lnhr;Ly22;
Host Species:Mouse
Reactivity:Human
Application:FCM
Isotype:Mouse IgG1, κ
Isotype Control:Genie Fluor 488 Mouse IgG1, κ Isotype Control[MOPC-21]
Form:Liquid
Conjugation:Genie Fluor488
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P14151
Gene ID:6402
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD62L is a 74-95 kD single chain type I glycoprotein referred to as L-selectin or LECAM-1. It is expressed on most peripheral blood B cells, subsets of T and NK cells, monocytes, granulocytes, and certain hematopoietic malignant cells. CD62L binds to carbohydrates present on certain glycoforms of CD34, glycam-1, and MAdCAM-1 and with a low affinity to anionic oligosaccharide sequences related to sialylated Lewis X (sLex, CD15s) through its C-type lectin domain. CD62L is important for the homing of naïve lymphocytes to high endothelial venules in peripheral lymph nodes and Peyer's patches. It also plays a role in leukocyte rolling on activated endothelial cells.

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