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GenieFluor 488 Anti-Human CD57 Antibody [HNK-1] (AGEL0270)

SKU:
AGEL0270
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Host Species:
Mouse
Isotype:
IgM
Clone:
HNK-1
Conjugation:
AF 488
Applications:
FC
$287 - $995
Frequently bought together:

Description

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GenieFluor 488 Anti-Human CD57 Antibody [HNK-1]

The Human CD57 Monoclonal Antibody (Alexa Fluor 488 Conjugated), also known as HNK-1 (AGEL0270), is a vital tool for researchers investigating immune cell markers. This monoclonal antibody, conjugated with Alexa Fluor 488, specifically recognizes the CD57 antigen expressed on human cells. CD57, a marker associated with natural killer cells and a subset of T cells, is involved in immune responses and has been linked to various diseases and conditions including infections, autoimmune disorders, and certain cancers. By utilizing this antibody, researchers can accurately identify and analyze CD57-expressing cells, enabling detailed investigations into immune responses and disease mechanisms.

With its high specificity and sensitivity, this antibody is suitable for a range of applications including flow cytometry, immunofluorescence, and immunohistochemistry. Its use can help elucidate the role of CD57 in immune function and disease progression, paving the way for advancements in immunology research and potential therapeutic interventions.

Product Title:GenieFluor 488 Anti-Human CD57 Antibody [HNK-1]
SKU:AGEL0270
Size:20 Tests, 100 Tests, 200 Tests
Clone No:HNK-1
Synonyms:HNK-1; NK-1; Leu-7;
Host Species:Mouse
Reactivity:Human
Application:FCM
Isotype:Mouse IgM, κ
Isotype Control:Genie Fluor 488 Mouse IgM, κ Isotype Control[MM-30]
Form:Liquid
Conjugation:Genie Fluor488
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Gene ID:27087
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD57, also known as HNK-1, NK-1, and Leu-7 is a 100-115 kD oligosaccharide antigenic determinant expressed on a variety of proteins, lipids, and chondroitin sulfate proteoglycans. CD57 is expressed on a subset of peripheral blood lymphocytes, including NK cells and CD8+ T cells, and is also expressed on neural cells and striated muscle. CD57 is not expressed on red blood cells, granulocytes, monocytes, or platelets. While the function of CD57 is unknown, binding to L-selectin, P-selectin, and a fragment of laminin suggests that CD57 may be involved in cell-matrix interactions. CD57 is increased in some disease states associated with CD4/CD8 imbalances (AIDS, autoimmune disease, viral infections, and allograft transplants).

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