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PE/Cyanine7 Anti-Human CD54 Antibody [15.2] (AGEL0910)

SKU:
AGEL0910
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Applications:
FC
€209 - €829
Frequently bought together:

Description

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PE/Cyanine7 Anti-Human CD54 Antibody [15.2]

The Human CD54 Monoclonal Antibody (PE/Cyanine7-Conjugated) is an essential tool for researchers studying CD54, a cell surface protein that plays a crucial role in immune responses and cell adhesion processes. This monoclonal antibody, conjugated with PE/Cyanine7 for fluorescence detection, specifically targets human CD54 and is validated for various applications, including flow cytometry and immunofluorescence.CD54, also known as intercellular adhesion molecule-1 (ICAM-1), is involved in mediating immune cell interactions, inflammation, and adhesion of leukocytes to endothelial cells. Its expression levels are often elevated in inflammatory conditions, making it a valuable marker for studying immune responses in diseases such as infections, autoimmune disorders, and inflammatory disorders.

By facilitating the detection and analysis of CD54 in different cell types, this antibody is indispensable for researchers investigating the mechanisms underlying immune cell activation and migration.Utilizing the Human CD54 Monoclonal Antibody (PE/Cyanine7-Conjugated) in your research can provide valuable insights into the role of CD54 in immune regulation and inflammatory processes, advancing our understanding of immune-mediated diseases and potentially contributing to the development of targeted therapies.

Product Title:PE/Cyanine7 Anti-Human CD54 Antibody [15.2]
SKU:AGEL0910
Size:20 Tests, 100 Tests, 200 Tests
Clone No:15.2
Synonyms:Intercellular adhesion molecule 1;Icam1;MALA-2;MyD10;CD54;Icam-1;
Host Species:Mouse
Reactivity:Human
Application:FCM
Isotype:Mouse IgG1, κ
Isotype Control:PE/Cyanine7 Mouse IgG1, κ Isotype Control[MOPC-21]
Form:Liquid
Conjugation:PE/Cyanine 7
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P05362
Gene ID:3383
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD54 is a 85-110 kD type I transmembrane protein also known as ICAM-1. It is expressed on activated endothelial cells, high endothelial venules, T and B cells, monocytes/macrophages, granulocytes, and dendritic cells. The expression of ICAM-1 can be released from the cell surface. CD54 plays a role in cellular adhesion and is involved in inflammation and leukocyte extravasation. CD54 has also been shown to be the major cellular receptor for rhinovirus. ICAM-1 binds to CD11a/CD18 (LFA-1), CD11b/CD18 (Mac-1), CD11c/CD18 (p150, 95) as well as hyaluronan and fibrinogen.

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