Description
Product Name: | Nanodisc Human CD47-Strep Protein |
SKU: | HDFP781 |
Size: | 10μg |
Target: | CD47 |
Tag: | C-Flag&Strep Tag |
Expression Host: | HEK293 |
Conjugate: | Unconjugated |
Synonyms: | IAP; MER6; OA3 |
Protein Families: | Druggable Genome, Transmembrane. |
Protein Description: | Human CD47-Strep full length protein-synthetic nanodisc |
Protein Pathways: | ECM-receptor interaction. |
Molecular Weight: | The human full length CD47-Strep protein has a MW of 35.2 kDa |
A membrane protein involved in the increase in intracellular calcium concentration that occurs upon cell adhesion to extracellular matrix. The encoded protein is also a receptor for the C-terminal cell binding domain of thrombospondin, and it may play a role in membrane transport and signal transduction. This gene has broad tissue distribution, and is reduced in expression on Rh erythrocytes.
Uniprot ID: | Q08722 |
Formulation & Reconstitution: | Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions. Do not use solvents with a pH below 6.5 or those containing high concentrations of divalent metal ions (greater than 5 mM) in subsequent experiments. |
Storage & Shipping: | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C(Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
Usage: | Research use only |