Human CD47/IAP/OA3 (C-Avi-6His) Biotinylated

Product Name:	Human CD47/IAP/OA3 (C-Avi-6His) Biotinylated
Product Code:	RPES6312
Size:	20µg
Species:	Human
Expression Host:	HEK293 Cells
Synonyms:	Leukocyte Surface Antigen CD47, Antigenic Surface Determinant Protein OA3, Integrin-Associated Protein, IAP, Protein MER6, CD47, MER6

Mol Mass:	16.4 kDa
AP Mol Mass:	33-44 kDa
Tag:	C-Avi-6His
Purity:	> 95 % as determined by reducing SDS-PAGE.
Endotoxin Level:	< 1.0 EU per μg of the protein as determined by the LAL method.
Bio Activity:	Testing in progress

Sequence:	Gln19-Pro139
Accession:	Q08722
Storage:	Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Shipping:	This product is provided as lyophilized powder which is shipped with ice packs.
Formulation:	Lyophilized from a 0.2 μm filtered solution of 10mMTris-Citrate, 150mM NaCl, pH 8.0. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Please refer to the specific buffer information in the pr
Reconstitution:	Please refer to the printed manual for detailed information.
Background:	CD47(Integrin-Associated Protein,IAP) is a 40 ‑ 60 kDa variably glycosylated atypical member of the immunoglobulin superfamily. The ubiquitously expressed CD47 binds to SIRP family members on macrophages, neutrophils, and T cells. CD47 is involved in the increase in intracellular calcium concentration that occurs upon cell adhesion to extracellular matrix. The protein is also a receptor for the C-terminal cell-binding domain of thrombospondin, and it may play a role in membrane transport and signal transduction. This protein has broad tissue distribution, and is reduced in expression on Rh erythrocytes.

Biological Role of GLP-1