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PE/Cyanine5 Anti-Human CD45RO Antibody [UCHL1] (AGEL1700)

SKU:
AGEL1700
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Applications:
FC
€139 - €469
Frequently bought together:

Description

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PE/Cyanine5 Anti-Human CD45RO Antibody [UCHL1]

The Human CD45RO Monoclonal Antibody (PE-Cyanine5 Conjugated, UCHL1) - AGEL1700, available from Assay Genie, is a specialized antibody designed for research purposes related to the CD45RO antigen, a marker of memory T cells in the human immune system. This monoclonal antibody, conjugated with PE-Cyanine5, offers high specificity and sensitivity in detecting CD45RO antigen expression in various cell types.The CD45RO antigen is an important protein involved in memory T cell function and differentiation, making it a key target for studies in immunology, infectious diseases, and immune-related disorders. By utilizing this antibody, researchers can accurately identify and analyze CD45RO-expressing cells, providing insights into immune memory responses and immune cell dynamics in different biological contexts.

With its validated performance in flow cytometry and immunofluorescence applications, the Human CD45RO Monoclonal Antibody (PE-Cyanine5 Conjugated, UCHL1) - AGEL1700 offers a reliable tool for investigating T cell-mediated immune responses, vaccine efficacy, and disease pathogenesis. This antibody is a valuable resource for researchers seeking to deepen their understanding of human immunology and T cell biology.

Product Title:PE/Cyanine5 Anti-Human CD45RO Antibody [UCHL1]
SKU:AGEL1700
Size:20 Tests, 100 Tests, 200 Tests
Clone No:UCHL1
Host Species:Mouse
Reactivity:Human
Application:FCM
Isotype:Mouse IgG2a, κ
Isotype Control:PE/Cyanine5 Mouse IgG2a, κ Isotype Control[C1.18.4]
Form:Liquid
Conjugation:PE/Cyanine 5
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Gene ID:5788
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD45RO is a 180 kD single chain membrane glycoprotein. It is a splice variant of tyrosine phosphatase CD45, lacking the A, B, and C determinants. The CD45RO isoform is expressed on activated and memory T cells, some B cell subsets, activated monocytes/macrophages, and granulocytes. CD45RO enhances both T cell receptor and B cell receptor signaling mediated activation. CD45 and its isoforms non-covalently associate with lymphocyte phosphatase-associated phosphoprotein (LPAP) on T and B lymphocytes. CD45 has been reported to be associated with several other cell surface antigens including CD1, CD2, CD3, and CD4. CD45 has also been reported to bind galectin-1 and CD22. CD45 isoform expression can change in response to cytokines.

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