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GenieFluor 488 Anti-Human CD45RO Antibody [UCHL1] (AGEL1704)

SKU:
AGEL1704
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Applications:
FC
€139 - €469
Frequently bought together:

Description

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GenieFluor 488 Anti-Human CD45RO Antibody [UCHL1]

The Human CD45RO Monoclonal Antibody (AF488 Conjugated) UCHL1 (AGEL1704) is a cutting-edge tool designed for researchers working in the field of immunology. This monoclonal antibody, conjugated with AF488 for fluorescent labeling, targets the CD45RO protein, a marker of memory T cells in the human immune system.With its high specificity and sensitivity, this antibody allows for accurate detection and analysis of CD45RO expression in various cell types, providing valuable insights into immune responses and memory T cell function. Its compatibility with fluorescence-based techniques such as flow cytometry and immunofluorescence microscopy makes it a versatile tool for investigating T cell populations in both normal and diseased states.

The CD45RO Monoclonal Antibody (AGEL1704) offers researchers the opportunity to delve deeper into the complexities of the human immune system, paving the way for advancements in the understanding and treatment of immune-related disorders, infectious diseases, and autoimmune conditions. Upgrade your research capabilities with this innovative antibody and unlock new possibilities in the realm of immunology.

Product Title:GenieFluor 488 Anti-Human CD45RO Antibody [UCHL1]
SKU:AGEL1704
Size:20 Tests, 100 Tests, 200 Tests
Clone No:UCHL1
Host Species:Mouse
Reactivity:Human
Application:FCM
Isotype:Mouse IgG2a, κ
Isotype Control:Genie Fluor 488 Mouse IgG2a, κ Isotype Control[C1.18.4]
Form:Liquid
Conjugation:Genie Fluor488
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Gene ID:5788
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD45RO is a 180 kD single chain membrane glycoprotein. It is a splice variant of tyrosine phosphatase CD45, lacking the A, B, and C determinants. The CD45RO isoform is expressed on activated and memory T cells, some B cell subsets, activated monocytes/macrophages, and granulocytes. CD45RO enhances both T cell receptor and B cell receptor signaling mediated activation. CD45 and its isoforms non-covalently associate with lymphocyte phosphatase-associated phosphoprotein (LPAP) on T and B lymphocytes. CD45 has been reported to be associated with several other cell surface antigens including CD1, CD2, CD3, and CD4. CD45 has also been reported to bind galectin-1 and CD22. CD45 isoform expression can change in response to cytokines.

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