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GenieFluor 647 Anti-Human CD45RA Antibody [HI100] (AGEL0961)

SKU:
AGEL0961
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Applications:
FC
€219 - €499

Description

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GenieFluor 647 Anti-Human CD45RA Antibody [HI100]

The Human CD45RA Monoclonal Antibody (AF647-conjugated, HI100, AGEL0961) is a valuable tool for researchers studying immune cell differentiation and function. This antibody, which specifically targets the CD45RA protein, is conjugated with AF647 for easy detection in flow cytometry and immunofluorescence experiments.CD45RA is a marker of naive T cells, which play a key role in the adaptive immune response. By targeting CD45RA, researchers can identify and characterize different subsets of T cells in various immune contexts.

This antibody, validated for use in human samples, offers a reliable way to analyze T cell populations in both healthy and diseased states.The versatility of this antibody makes it ideal for a wide range of research applications, including immunology, cancer biology, and autoimmune disease studies. Its ability to specifically bind to CD45RA in human samples ensures accurate and reproducible results, making it a valuable tool for scientists aiming to unravel the complexities of the immune system.

Product Title:GenieFluor 647 Anti-Human CD45RA Antibody [HI100]
SKU:AGEL0961
Size:20 Tests, 100 Tests, 200 Tests
Clone No:HI100
Synonyms:Receptor-type tyrosine-protein phosphatase C;Ptprc;L-CA;Ly-5;T200;CD45;
Host Species:Mouse
Reactivity:Human
Application:FCM
Isotype:Mouse IgG2b, κ
Isotype Control:Genie Fluor 647 Mouse IgG2b, κ Isotype Control[MPC-11]
Form:Liquid
Conjugation:Genie Fluor647
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P08575
Gene ID:5788
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD45RA is a 205-220 kD single chain type I glycoprotein. It is an exon 4 splice variant of the tyrosine phosphatase CD45. The CD45RA isoform is expressed on resting/naïve T cells, medullary thymocytes, B cells and monocytes. CD45RA enhances both T cell receptor and B cell receptor signaling. CD45 non-covalently associates with lymphocyte phosphatase-associated phosphoprotein (LPAP) on T and B lymphocytes. CD45 has been reported to be associated with several other cell surface antigens including CD1, CD2, CD3, and CD4. CD45 has also been reported to bind galectin-1. CD45 isoform expression can change in response to cytokines.

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