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PE/Cyanine7 Anti-Human CD45 Antibody [HI30] (AGEL1682)

SKU:
AGEL1682
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Applications:
FC
€239 - €519
Frequently bought together:

Description

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PE/Cyanine7 Anti-Human CD45 Antibody [HI30]

The Human CD45 Monoclonal Antibody PE/Cyanine7 Conjugated (Clone HI30) from Assay Genie (Product Code: AGL1682) is a cutting-edge tool designed for precision research in immunology and cell biology. This high-quality antibody is meticulously crafted to target CD45, a crucial cell surface marker that plays a pivotal role in immune system function.With its specific conjugation to PE/Cyanine7, this monoclonal antibody offers exceptional sensitivity and accuracy in detecting CD45 protein expression in human samples. The validated performance of this antibody in flow cytometry and fluorescence-based assays ensures reliable and reproducible results for your experiments.

CD45, also known as leukocyte common antigen, is integral for immune cell signaling and activation, making it a key target in immunological studies and clinical research. By utilizing the Human CD45 Monoclonal Antibody PE/Cyanine7 Conjugated (Clone HI30), researchers can delve deeper into immune cell subpopulations, immune responses, and disease mechanisms, paving the way for advancements in immunotherapy, autoimmune disease research, and cancer immunology.Enhance your research capabilities with this advanced antibody from Assay Genie, unlocking new insights into the intricate workings of the immune system and its implications for human health.

Product Title:PE/Cyanine7 Anti-Human CD45 Antibody [HI30]
SKU:AGEL1682
Size:20 Tests, 100 Tests, 200 Tests
Clone No:HI30
Synonyms:Receptor-type tyrosine-protein phosphatase C;Ptprc;L-CA;Ly-5;T200;CD45;
Host Species:Mouse
Reactivity:Human
Application:FCM
Isotype:Mouse IgG1, κ
Isotype Control:PE/Cyanine7 Mouse IgG1, κ Isotype Control[MOPC-21]
Form:Liquid
Conjugation:PE/Cyanine 7
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P08575
Gene ID:5788
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD45 is a 180 - 240 kD single chain type I membrane glycoprotein also known as leukocyte common antigen (LCA) and T200. It is a tyrosine phosphatase expressed on the plasma membrane of all hematopoietic cells, except erythrocytes or platelets. CD45 is a signaling molecule that regulates a variety of cellular processes including cell growth, differentiation, cell cycle, and oncogenic transformation. CD45 plays a critical role in T and B cell antigen receptor-mediated activation by dephosphorylating substrates including p56Lck, p59Fyn, and other Src family kinases. CD45 non-covalently associates with lymphocyte phosphatase-associated phosphoprotein (LPAP) on T and B lymphocytes. CD45 has been reported to bind galectin-1 and to be associated with several other cell surface antigens including CD1, CD2, CD3, and CD4.

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