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GenieFluor 647 Anti-Human CD45 Antibody [HI30] (AGEL1686)

SKU:
AGEL1686
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Applications:
FC
€139 - €469
Frequently bought together:

Description

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GenieFluor 647 Anti-Human CD45 Antibody [HI30]

The Human CD45 Monoclonal Antibody (AF647 Conjugated, HI30, AGEL1686) offered by Assay Genie is a cutting-edge tool for researchers studying the CD45 protein in human samples. The antibody is specifically designed to bind to CD45, a key cell surface marker involved in immune cell activation and signaling.With its high specificity and reactivity, this antibody is an essential tool for a range of research applications, including flow cytometry, immunofluorescence, and immunohistochemistry. By targeting CD45, researchers can effectively identify and characterize immune cell populations in various tissues and biological samples.

This monoclonal antibody offers exceptional performance and reliability for studying the role of CD45 in immune responses, inflammation, and other physiological processes. Its conjugation with AF647 allows for sensitive detection and visualization of CD45-expressing cells, providing valuable insights into immune system function and dysfunction.For scientists engaged in immunology, cell biology, and disease research, the Human CD45 Monoclonal Antibody (AF647 Conjugated, HI30, AGEL1686) is an indispensable tool for advancing our understanding of immune cell biology and its implications for health and disease.

Product Title:GenieFluor 647 Anti-Human CD45 Antibody [HI30]
SKU:AGEL1686
Size:20 Tests, 100 Tests, 200 Tests
Clone No:HI30
Synonyms:Receptor-type tyrosine-protein phosphatase C;Ptprc;L-CA;Ly-5;T200;CD45;
Host Species:Mouse
Reactivity:Human
Application:FCM
Isotype:Mouse IgG1, κ
Isotype Control:Genie Fluor 647 Mouse IgG1, κ Isotype Control[MOPC-21]
Form:Liquid
Conjugation:Genie Fluor647
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P08575
Gene ID:5788
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD45 is a 180 - 240 kD single chain type I membrane glycoprotein also known as leukocyte common antigen (LCA) and T200. It is a tyrosine phosphatase expressed on the plasma membrane of all hematopoietic cells, except erythrocytes or platelets. CD45 is a signaling molecule that regulates a variety of cellular processes including cell growth, differentiation, cell cycle, and oncogenic transformation. CD45 plays a critical role in T and B cell antigen receptor-mediated activation by dephosphorylating substrates including p56Lck, p59Fyn, and other Src family kinases. CD45 non-covalently associates with lymphocyte phosphatase-associated phosphoprotein (LPAP) on T and B lymphocytes. CD45 has been reported to bind galectin-1 and to be associated with several other cell surface antigens including CD1, CD2, CD3, and CD4.

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