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GenieFluor 488 Anti-Human CD45 Antibody [HI30] (AGEL1685)

SKU:
AGEL1685
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Applications:
FC
€189 - €469
Frequently bought together:

Description

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GenieFluor 488 Anti-Human CD45 Antibody [HI30]

The Human CD45 Monoclonal Antibody (AF488-conjugated, HI30, AGEL1685) offered by AssayGenie is a cutting-edge tool for research in immunology and cell biology. This monoclonal antibody, specifically targeting the CD45 antigen found on human cells, is conjugated with AF488 for fluorescence applications, allowing for easy and precise detection in flow cytometry, immunofluorescence, and immunohistochemistry.The CD45 antigen, also known as the leukocyte common antigen, is a crucial marker for identifying various immune cell populations, including T cells, B cells, and natural killer cells. The HI30 monoclonal antibody is highly specific and sensitive, providing reliable results in experimental settings.

Its validation for human samples ensures accurate and consistent performance, making it an essential tool for studying immune cell subsets and their functions.Researchers investigating immune responses, hematopoiesis, inflammation, and related diseases will find the Human CD45 Monoclonal Antibody (AF488-conjugated, HI30, AGEL1685) invaluable for their studies. Its versatility and reliability make it a valuable asset for laboratories and institutions conducting cutting-edge research in immunology and beyond.

Product Title:GenieFluor 488 Anti-Human CD45 Antibody [HI30]
SKU:AGEL1685
Size:20 Tests, 100 Tests, 200 Tests
Clone No:HI30
Synonyms:Receptor-type tyrosine-protein phosphatase C;Ptprc;L-CA;Ly-5;T200;CD45;
Host Species:Mouse
Reactivity:Human
Application:FCM
Isotype:Mouse IgG1, κ
Isotype Control:Genie Fluor 488 Mouse IgG1, κ Isotype Control[MOPC-21]
Form:Liquid
Conjugation:Genie Fluor488
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P08575
Gene ID:5788
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD45 is a 180 - 240 kD single chain type I membrane glycoprotein also known as leukocyte common antigen (LCA) and T200. It is a tyrosine phosphatase expressed on the plasma membrane of all hematopoietic cells, except erythrocytes or platelets. CD45 is a signaling molecule that regulates a variety of cellular processes including cell growth, differentiation, cell cycle, and oncogenic transformation. CD45 plays a critical role in T and B cell antigen receptor-mediated activation by dephosphorylating substrates including p56Lck, p59Fyn, and other Src family kinases. CD45 non-covalently associates with lymphocyte phosphatase-associated phosphoprotein (LPAP) on T and B lymphocytes. CD45 has been reported to bind galectin-1 and to be associated with several other cell surface antigens including CD1, CD2, CD3, and CD4.

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