The Human CD44 Monoclonal Antibody (AF488 Conjugated) (J110) is a powerful tool for researchers studying CD44, a cell surface protein involved in cell adhesion, migration, and signaling processes. This monoclonal antibody, conjugated with AF488 for fluorescence applications, has been developed specifically for use in immunofluorescence assays, flow cytometry, and other cellular imaging techniques.CD44 is a multifunctional glycoprotein that plays a key role in various physiological and pathological processes, including inflammation, cancer metastasis, and stem cell homing. By targeting CD44 with this highly-specific monoclonal antibody, researchers can visualize and quantify the expression and distribution of CD44 in different cell types and tissues.
This enables deeper insights into the role of CD44 in cellular interactions and disease progression.The AF488 conjugation of this monoclonal antibody allows for easy and sensitive detection of CD44 in experimental samples, providing researchers with a versatile tool for investigating the function and regulation of this important protein. With its high specificity and sensitivity, the Human CD44 Monoclonal Antibody (AF488 Conjugated) (J110) is a valuable resource for studies in the fields of immunology, cancer biology, and regenerative medicine. Unlock the potential of CD44 research with this versatile antibody.
Genie Fluor 488 Rat IgG2a, κ Isotype Control[2A3]
Form:
Liquid
Conjugation:
Genie Fluor488
Recommended Use:
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P16070
Gene ID:
960
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD44 is a 80-95 kD glycoprotein also known as Hermes, Pgp1, H-CAM, or HUTCH. It is expressed on all leukocytes, endothelial cells, hepatocytes, and mesenchymal cells. As B and T cells become activated or progress to the memory stage, CD44 expression increases from a low or mid level of intensity to high expression levels. Thus, CD44 has been reported to be a valuable marker for memory cell subsets. CD44 is an adhesion molecule involved in leukocyte attachment to and rolling on endothelial cells, homing to peripheral lymphoid organs and to the sites of inflammation, and leukocyte aggregation.