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GenieFluor 488 Anti-Human CD41 Antibody [HIP8] (AGEL0327)

SKU:
AGEL0327
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Host Species:
Mouse
Isotype:
IgG1
Clone:
HIP8
Conjugation:
AF 488
Applications:
FC
€249 - €779
Frequently bought together:

Description

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GenieFluor 488 Anti-Human CD41 Antibody [HIP8]

The Human CD41 Monoclonal Antibody (ALEXA FLUOR 488 Conjugated) - HIP8 (AGEL0327) is a powerful tool for researchers studying the CD41 antigen, a protein found on the surface of platelets. This monoclonal antibody, conjugated with ALEXA FLUOR 488 for fluorescent detection, offers precise targeting and visualization of CD41 in human samples.CD41, also known as integrin alpha IIb, plays a vital role in platelet aggregation and adhesion, essential processes in hemostasis and thrombosis. By specifically binding to CD41, this antibody allows researchers to track platelet activity and location in various experimental settings.

It is validated for use in techniques such as flow cytometry, immunofluorescence, and microscopy, providing flexibility for diverse research applications.Understanding the functions and regulation of CD41 is key for advancements in vascular biology, coagulation disorders, and cardiovascular research. The Human CD41 Monoclonal Antibody (ALEXA FLUOR 488 Conjugated) - HIP8 (AGEL0327) offers reliable and precise detection of CD41, enabling researchers to delve deeper into the intricate mechanisms of platelet function and thrombotic processes.

Product Title:GenieFluor 488 Anti-Human CD41 Antibody [HIP8]
SKU:AGEL0327
Size:20 Tests, 100 Tests, 200 Tests
Clone No:HIP8
Synonyms:Integrin alpha-Iib;ITGA2B;GPalpha Iib;GPIIb;Platelet membrane glycoprotein Iib;CD41;GP2B; ITGAB;
Host Species:Mouse
Reactivity:Human
Application:FCM
Isotype:Mouse IgG1, κ
Isotype Control:Genie Fluor 488 Mouse IgG1, κ Isotype Control[MOPC-21]
Form:Liquid
Conjugation:Genie Fluor488
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P08514
Gene ID:3674
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD41 is a 125/25 kD α subunit of the gpIIb/IIIa (CD41/CD61) complex. CD41 is a heterodimer composed of a heavy chain (gpIIbα) and light chain (gpIIbβ) linked by a single disulfide bond. It is a member of the integrin family primarily expressed on platelets and megakaryocytes. CD41 has been reported to be involved with platelet aggregation and platelet attachment to the ECM. CD41/CD61 complex acts as the receptor for fibrinogen, fibronectin, Von Willebrand factor and thrombin.

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