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GenieFluor 647 Anti-Human CD40 Antibody [G28.5] (AGEL2100)

SKU:
AGEL2100
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Applications:
FC
€219 - €749

Description

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GenieFluor 647 Anti-Human CD40 Antibody [G28.5]

The Human CD40 Monoclonal Antibody (AF647-conjugated G28-5) AGEL2100 is a powerful tool for researchers studying CD40, a cell surface receptor involved in immune responses and inflammation. This monoclonal antibody, conjugated with AF647 for fluorescence detection, specifically targets human CD40 and is validated for various applications including flow cytometry and immunofluorescence.CD40 is a key molecule in the immune system, playing a crucial role in the activation of B cells and antigen-presenting cells. By targeting CD40 with this antibody, researchers can gain valuable insights into the function and regulation of immune responses, particularly in the context of infectious diseases, autoimmune disorders, and cancer.

With its high specificity and sensitivity, the Human CD40 Monoclonal Antibody (AF647-conjugated G28-5) AGEL2100 is an essential tool for investigating the role of CD40 in immune signaling pathways and potential therapeutic targets. Its use in research can contribute to the development of novel treatments and interventions for various immune-related conditions.

Product Title:GenieFluor 647 Anti-Human CD40 Antibody [G28.5]
SKU:AGEL2100
Size:20 Tests, 100 Tests, 200 Tests
Clone No:G28.5
Synonyms:Bp50;CDw40;CD40L receptor;TNFRSF5;
Host Species:Mouse
Reactivity:Human
Application:FCM
Isotype:Mouse IgG1, κ
Isotype Control:Genie Fluor 647 Mouse IgG1, κ Isotype Control[MOPC-21]
Form:Liquid
Conjugation:Genie Fluor647
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P25942
Gene ID:958
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD40 is a 48 kD type I glycoprotein also known as BP50. It is a member of the TNFR superfamily primarily expressed on B cells, macrophages, follicular dendritic cells, endothelial cells, fibroblasts, and at low levels on plasma cells. CD40 has been reported to be involved in B cell differentiation, costimulation, isotype class-switching, and protection of B cells from apoptosis. Additionally, CD40 is important for T cell-B cell interactions. The ligand of CD40 is CD154 (CD40 ligand).

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